Evidence map›Paper›PMID 39349310›Full record

ArticleAJNR. American journal of neuroradiology2025

Density and Time Characteristics of CSF-Venous Fistulas on CT Myelography in Patients with Spontaneous Intracranial Hypotension.

Diogo G L Edelmuth, Timothy J Amrhein, Peter G Kranz

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Article in AJNR. American journal of neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Optimizing density of intrathecal contrast at digital subtraction myelography: Evaluation of differing needle characteristics and injection rates in a phantom.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Diogo G L EdelmuthFrom the Department of Radiology and Oncology (D.G.L.E.), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.ORCID 0000-0003-0567-0823
Timothy J AmrheinDuke University Medical Center (T.J.A., P.G.K.), Durham, North Carolina.ORCID 0000-0002-9354-9486
Peter G KranzDuke University Medical Center (T.J.A., P.G.K.), Durham, North Carolina.ORCID 0000-0001-5410-7135

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe conspicuity of CSF-venous fistulas (CVFs) on specialized myelographic imaging protocols varies, and the factors that determine their visibility have not yet been extensively studied. The purpose of this study was to determine the relative effect of 2 variables on CVF visibility: timing of imaging and intrathecal contrast attenuation. MATERIALS AND

methodsA retrospective cohort of 24 patients with spontaneous intracranial hypotension due to a CVF who underwent a total of 34 CT myelographies was studied. All CTM acquisitions that included the level of the known definite CVF were evaluated for 1) time passed after injection of contrast, 2) attenuation of the adjacent subarachnoid space, 3) subjective visibility of the CVF on that series, 4) attenuation of the corresponding draining vein, and 5) contrast dose used.

resultsA total of 131 acquisitions included the level of the known CVFs. Attenuation values of the thecal sac were significantly higher in acquisitions where the CVFs were definitely visible (average 2283 HU) than in acquisitions where the CVFs were equivocal or not visible (764 HU and 583 HU, respectively). No significant difference was shown in the timing of the acquisitions between the 3 groups (12.8 minutes, 20.4 minutes, and 17.5 minutes, respectively). Multivariate linear regression showed thecal sac attenuation to be the only independent predictor of the attenuation of the CVF draining vein. Time passed after contrast injection was not independently correlated.

conclusionsIntrathecal contrast attenuation has a strong positive relationship with the visibility of CVF. Timing of the acquisition was not an independent predictor of CVF visibility under our acquisition protocol.

Indexed as

Intracranial HypotensionMyelographyTomography, X-Ray ComputedAdultAgedContrast MediaFemaleHumansMaleMiddle AgedReproducibility of ResultsRetrospective StudiesContrast Media

Identifiers

PMID39349310
PMCPMC11979859

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.