Evidence map›Paper›PMID 39348891›Full record

Trial reportJMIR cancer2024

Exploring Racial Disparities in Awareness and Perceptions of Oncology Clinical Trials: Cross-Sectional Analysis of Baseline Data From the mychoice Study.

Ariel Hoadley, Linda Fleisher, Cassidy Kenny, Patrick Ja Kelly, Xinrui Ma, Jingwei Wu, Carmen Guerra, Amy E Leader, Mohammed Alhajji, Paul D'Avanzo and 2 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in JMIR cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ariel HoadleyDepartment of Social and Behavioral Sciences, Temple University College of Public Health, Philadelphia, PA, United States.ORCID 0000-0003-1360-0358
Linda FleisherCancer Prevention and Control, Fox Chase Cancer Center, Philadelphia, PA, United States.ORCID 0000-0002-6911-0756
Cassidy KennyCancer Prevention and Control, Fox Chase Cancer Center, Philadelphia, PA, United States.ORCID 0009-0006-6091-1537
Patrick Ja KellyDepartment of Social and Behavioral Sciences, Temple University College of Public Health, Philadelphia, PA, United States.ORCID 0000-0003-1462-1150
Xinrui MaDepartment of Epidemiology and Biostatistics, Temple University College of Public Health, Philadelphia, PA, United States.ORCID 0000-0002-7970-3387
Jingwei WuDepartment of Epidemiology and Biostatistics, Temple University College of Public Health, Philadelphia, PA, United States.ORCID 0000-0003-1003-619X
Carmen GuerraAbramson Cancer Center, University of Pennsylvania Medical Center, Philadelphia, PA, United States.ORCID 0000-0001-6349-9142
Amy E LeaderDivision of Population Science, Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, United States.ORCID 0000-0002-9514-3631
Mohammed AlhajjiDepartment of Social and Behavioral Sciences, Temple University College of Public Health, Philadelphia, PA, United States.ORCID 0000-0001-6199-449X
Paul D'AvanzoDepartment of Social and Behavioral Sciences, Temple University College of Public Health, Philadelphia, PA, United States.ORCID 0000-0002-3007-0099
Zoe LandauCancer Prevention and Control, Fox Chase Cancer Center, Philadelphia, PA, United States.ORCID 0009-0000-0375-9715
Sarah Bauerle BassDepartment of Social and Behavioral Sciences, Temple University College of Public Health, Philadelphia, PA, United States.ORCID 0000-0003-2742-1609

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBlack/African American adults are underrepresented in oncology clinical trials in the United States, despite efforts at narrowing this disparity.

objectiveThis study aims to explore differences in how Black/African American oncology patients perceive clinical trials to improve support for the clinical trial participation decision-making process.

methodsAs part of a larger randomized controlled trial, a total of 244 adult oncology patients receiving active treatment or follow-up care completed a cross-sectional baseline survey on sociodemographic characteristics, clinical trial knowledge, health literacy, perceptions of cancer clinical trials, patient activation, patient advocacy, health care self-efficacy, decisional conflict, and clinical trial intentions. Self-reported race was dichotomized into Black/African American and non-Black/African American. As appropriate, 2-tailed t tests and chi-square tests of independence were used to examine differences between groups.

resultsBlack/African American participants had lower clinical trial knowledge (P=.006), lower health literacy (P<.001), and more medical mistrust (all P values <.05) than non-Black/African American participants. While intentions to participate in a clinical trial, if offered, did not vary between Black/African American and non-Black/African American participants, Black/African American participants indicated lower awareness of clinical trials, fewer benefits of clinical trials, and more uncertainty around clinical trial decision-making (all P values <.05). There were no differences for other variables.

conclusionsDespite no significant differences in intent to participate in a clinical trial if offered and high overall trust in individual health care providers among both groups, beliefs persist about barriers to and benefits of clinical trial participation among Black/African American patients. Findings highlight specific ways that education and resources about clinical trials could be tailored to better suit the informational and decision-making needs and preferences of Black/African American oncology patients.

Indexed as

Black or African AmericanNeoplasmsAdultAgedClinical Trials as TopicCross-Sectional StudiesDecision MakingFemaleHealthcare DisparitiesHealth Knowledge, Attitudes, PracticeHealth LiteracyHumansMaleMiddle AgedPatient ParticipationUnited Statescancerdecision-makingmedical mistrustoncology clinical trialracial disparity

Identifiers

PMID39348891
PMCPMC11474127

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.