Evidence map›Paper›PMID 39348798›Full record

ArticleDigestive diseases (Basel, Switzerland)2024

Esophageal Varices as an Independent Predictor of Fatal Outcomes after Balloon-Occluded Retrograde Transvenous Obliteration in Patients with Hepatic Encephalopathy.

Shuichiro Iwasaki, Haruki Uojima, Shinya Sakita, Sakue Masuda, Kousuke Kubota, Tomoaki Fujikawa, Tomomi Okubo, Toru Setsu, Norio Itokawa, Yoshihiro Furuichi and 9 more

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In one paragraph

Article in Digestive diseases (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Shuichiro IwasakiDepartment of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Haruki UojimaDepartment of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Shinya SakitaDepartment of Gastroenterology, Yokohama City Minato Red Cross Hospital, Yokohama, Japan.
Sakue MasudaDepartment of Gastroenterology, Shonan Kamakura General Hospital, Kamakura, Japan.
Kousuke KubotaDepartment of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Tomoaki FujikawaDepartment of Gastroenterology, Shonan Fujisawa Tokushukai Hospital, Fujisawa, Japan.
Tomomi OkuboDivision of Gastroenterology, Department of Internal Medicine, Nippon Medical School Chiba Hokusoh Hospital, Inzai, Japan.
Toru SetsuDivision of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Norio ItokawaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Nippon Medical School Hospital, Tokyo, Japan.
Yoshihiro FuruichiDepartment of Clinical Laboratory and Endoscopy, Tokyo Women's Medical University Adachi Medical Center, Tokyo, Japan.
Yoshitaka AraseDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan.
Toshiki TukiyamaCenter of Interventional Radiology, Shonan Kamakura General Hospital, Kamakura, Japan.
Kaoru FujiiDepartment of Diagnostic Radiology, Kitasato University School of Medicine, Sagamihara, Japan.
Hisashi HidakaDepartment of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Masanori AtsukawaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Nippon Medical School Hospital, Tokyo, Japan.
Tatehiro KagawaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan.
Makoto KakoDepartment of Gastroenterology, Shonan Kamakura General Hospital, Kamakura, Japan.
Shuji TeraiDivision of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Chika KusanoDepartment of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Sagamihara, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe objective of this study was to evaluate esophageal varices (EVs) as predictors of poor prognosis with low tolerability after balloon-occluded retrograde transvenous obliteration (BRTO) in patients with overt hepatic encephalopathy (HE).

methodsThis study retrospectively enrolled 107 patients who underwent BRTO for uncontrollable overt HE. The enrolled patients were divided into two groups based on the presence of EVs using propensity matching. The present study assessed the technical success rate and safety of BRTO in both the groups. Further, the event-free survival, HE-free survival, and the overall survival (OS) were compared between the two groups. Event-free survival was defined as the time period during which the patients did not developed complications related to portal hypertension, including EVs, hepatic ascites, and portal vein thrombosis.

resultsAfter propensity matching, the EV and non-EV groups had 37 and 36 patients, respectively. Only 1 patient experienced an unsuccessful procedure in the EV group. Procedure-related adverse events in the EV group and non-EV group occurred in 11 and 7 patients, respectively (p = 0.417). The event-free survival after BRTO in the EV and non-EV group were 1,283 (95% CI: 798-1,767) days and 2,257 (1,722-2,792) days, respectively. Event-free survival was significantly worse in the EV group than in the non-EV group (p = 0.014). Furthermore, the EV group experienced worse OS than the non-EV group (p = 0.001 and p < 0.001, respectively).

conclusionsThe presence of EVs could potentially be associated with a higher risk of adverse outcomes or mortality after BRTO treatment in individuals with HE.

Indexed as

Balloon OcclusionEsophageal and Gastric VaricesHepatic EncephalopathyAgedFemaleHumansMaleMiddle AgedPrognosisPropensity ScoreRetrospective StudiesTreatment OutcomeBalloon-occluded retrograde transvenous obliterationEsophageal varicesHepatic encephalopathyPoor prognosisPortosystemic shunt

Identifiers

PMID39348798
PMCPMC11614304

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.