Evidence map›Paper›PMID 39348562›Full record

ArticleJournal of natural products2024

Further Probing the Properties of a Unique Sponge-derived Alkaloid Through the Isolation of a New (-)-(5

Joe A Gerke, Sofia F Odron, Juri Kim, Naibedya Dutta, Jacqueline G Clarke, Joseph Media, David A Coppage, Maria Oorloff, Athena Alcala, Gilberto Garcia and 8 more

Abstract read
In one paragraph

Article in Journal of natural products, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Marine natural products.Natural product reports · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Joe A GerkeDepartment of Natural Sciences & Mathematics, Dominican University of California, San Rafael, California 94901, United States.
Sofia F OdronDepartment of Natural Sciences & Mathematics, Dominican University of California, San Rafael, California 94901, United States.
Juri KimLeonard Davis School of Gerontology, University of Southern California, Los Angeles, California 90089, United States.
Naibedya DuttaLeonard Davis School of Gerontology, University of Southern California, Los Angeles, California 90089, United States.
Jacqueline G ClarkeDepartment of Natural Sciences & Mathematics, Dominican University of California, San Rafael, California 94901, United States.
Joseph MediaJosephine Ford Cancer Center, Division of Hematology and Oncology, Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan 48202, United States.
David A CoppageDepartment of Chemistry, One Shields Ave, University of California, Davis, California 95616, United States.
Maria OorloffLeonard Davis School of Gerontology, University of Southern California, Los Angeles, California 90089, United States.
Athena AlcalaLeonard Davis School of Gerontology, University of Southern California, Los Angeles, California 90089, United States.
Gilberto GarciaLeonard Davis School of Gerontology, University of Southern California, Los Angeles, California 90089, United States.
Marissa E F KangDepartment of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, California 95064, United States.
Cy L GerkeDepartment of Natural Sciences & Mathematics, Dominican University of California, San Rafael, California 94901, United States.
Jacob C PetersonDepartment of Natural Sciences & Mathematics, Dominican University of California, San Rafael, California 94901, United States.
Joseph D MorrisDepartment of Natural Sciences & Mathematics, Dominican University of California, San Rafael, California 94901, United States.ORCID 0000-0001-5218-425X
Ryo Higuchi-SanabriaLeonard Davis School of Gerontology, University of Southern California, Los Angeles, California 90089, United States.
Frederick A ValerioteJosephine Ford Cancer Center, Division of Hematology and Oncology, Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan 48202, United States.
Phillip CrewsDepartment of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, California 95064, United States.ORCID 0000-0002-9061-9549
Tyler A JohnsonDepartment of Natural Sciences & Mathematics, Dominican University of California, San Rafael, California 94901, United States.ORCID 0000-0001-6816-726X

Funding

USC Geroscience Training in the Biology of AgingT32AG052374 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Sean P CURRAN · 2016 to 2026
$5.3M
When actin’s not actin like actin: Nuclear actin impacts transcription and agingR01AG079806 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Ryo Higuchi-Sanabria · 2024 to 2026
$1.9M
Acquisition of a Cryoprobe and Related Accessories for a 600 MHz NMR Spectrometer to Support Health Research Activities at the University of California, BerkeleyS10OD024998 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI HARTWIG, JOHN F · 2018 to 2018
$265k
NIA NIH HHS R01 AG079806NIA NIH HHS T32 AG052374NIH HHS S10 OD024998
6 · The paper itself

Abstract

Scale-up isolation of (+)-(5

Indexed as

AlkaloidsPoriferaThiazolesAnimalsAntineoplastic AgentsCaenorhabditis elegansDrug Screening Assays, AntitumorHep G2 CellsHumansMiceMolecular StructureStereoisomerismAlkaloidsAntineoplastic AgentsThiazoles

Identifiers

PMID39348562
PMCPMC11534373

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.