Evidence map›Paper›PMID 39348488›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2024

Total Synthesis of Tosyl-Samroiyotmycin A and Its Biological Profiling.

Benedikt Kolb, Fabian Schmid, Jessica Weng, Luca Altevogt, Ruben Pereira Rebelo, Bianca Wank, Angelika Baro, Anna Zens, Aditya Shekhar, Ursula Bilitewski and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Total Synthesis of Tosyl-Samroiyotmycin A and Its Biological Profiling.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Benedikt KolbInstitut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, D-70569, Stuttgart, Germany.
Fabian SchmidInstitut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, D-70569, Stuttgart, Germany.
Jessica WengInstitut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, D-70569, Stuttgart, Germany.
Luca AltevogtInstitut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, D-70569, Stuttgart, Germany.
Ruben Pereira RebeloInstitut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, D-70569, Stuttgart, Germany.
Bianca WankInstitut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, D-70569, Stuttgart, Germany.
Angelika BaroInstitut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, D-70569, Stuttgart, Germany.
Anna ZensInstitut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, D-70569, Stuttgart, Germany.ORCID https://orcid.org/0000-0003-0348-2861
Aditya ShekharAG Compound Profiling and Screening, Helmholtz Zentrum für Infektionsforschung, Inhoffenstr. 7, D-38124, Braunschweig, Germany.
Ursula BilitewskiAG Compound Profiling and Screening, Helmholtz Zentrum für Infektionsforschung, Inhoffenstr. 7, D-38124, Braunschweig, Germany.
Sibylle SaxParasite Chemotherapy, Swiss Tropical and Public Health Institute, University of Basel, Kreuzstr. 2, CH-4123 Allschwil, Basel, Switzerland.
Sergio WittlinParasite Chemotherapy, Swiss Tropical and Public Health Institute, University of Basel, Kreuzstr. 2, CH-4123 Allschwil, Basel, Switzerland.
Dale TaylorDrug Discovery and Development Centre (H3D), Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Observatory, 7925, South Africa.
Rudolf MüllerDrug Discovery and Development Centre (H3D), Department of Chemistry, University of Cape Town, Rondebosch, 7700, South Africa.
Sabine LaschatInstitut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, D-70569, Stuttgart, Germany.

Funding

Deutsche Forschungsgemeinschaft HBGFDeutsche Forschungsgemeinschaft INST 41/897-1 FUGGFonds der Chemischen IndustrieMinisterium für Wissenschaft, Forschung und Kunst Baden-Württemberg
6 · The paper itself

Abstract

A total synthesis of the enantiopure syn,syn-tosyl-samroiyotmycin A, a C

Indexed as

AntimalarialsPlasmodium falciparumBiological ProductsMacrolidesOxazolidinonesStereoisomerismStructure-Activity RelationshipAntimalarialsBiological ProductsMacrolidesOxazolidinonesAntimalarial activityBiological profilingMacrocyclesMacrodiolideNatural products

Identifiers

PMID39348488
PMCPMC11653242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.