Evidence map›Paper›PMID 39348042›Full record

ReviewGeroScience2025

A review of antioxidant strategies to improve reproduction in aging male broiler breeders.

Sarallah Yarmohammadi Barbarestani, Firooz Samadi, Mojtaba Zaghari, Soroush Khademian, Zarbakht Ansari Pirsaraei, John P Kastelic

Abstract readReview
In one paragraph

Review in GeroScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sarallah Yarmohammadi BarbarestaniDepartment of Animal and Poultry Physiology, Faculty of Animal Science, Gorgan University of Agricultural Science and Natural Resources, Gorgan, Golestan, Iran. y.sarallah@yahoo.com.
Firooz SamadiDepartment of Animal and Poultry Physiology, Faculty of Animal Science, Gorgan University of Agricultural Science and Natural Resources, Gorgan, Golestan, Iran.
Mojtaba ZaghariDepartment of Animal Science, College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran.
Soroush KhademianFaculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Zarbakht Ansari PirsaraeiDepartment of Animal Science, Sari Agricultural Science and Natural Resource University, Sari, Mazandaran, Iran.
John P KastelicFaculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada. jpkastel@ucalgary.ca.ORCID 0000-0003-4607-3355

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As only 10% of the broiler breeder flock is roosters, their fertility is very important. The rooster sperm plasma membrane has high concentrations of polyunsaturated fatty acids that are sensitive to oxidative stress. Lipid peroxidation can change membrane structure, permeability, and fluidity, adversely affecting the acrosome reaction and fertility. Aging roosters have decreases in sexual behavior, serum androgen concentrations, sperm quantity and quality, and fertility. Low fertility in aging roosters is attributed to an imbalanced testicular oxidant-antioxidant system, with increased reactive oxygen species (ROS) damaging spermatogenic epithelium. However, antioxidant components can enhance antioxidant defenses in aging broiler breeder roosters. Protection against oxidative damage, particularly in the testes, improves reproductive hormone concentrations, testicular histology, sperm membrane function, and mitochondrial activity and thereby improves semen volume, sperm concentration, viability, motility, and sperm polyunsaturated fatty acid content, sperm-egg penetration, fertility, and reproductive performance. This review summarizes antioxidants that could improve fertility and reproductive performance and delay or prevent age-related declines in broiler breeder roosters, with benefits for poultry production.

Indexed as

AgingAntioxidantsChickensReproductionAnimalsFertilityMaleOxidative StressSpermatozoaTestisAntioxidantsFertilityOxidative stressReproductive senescenceRoostersSperm

Identifiers

PMID39348042
PMCPMC11872827

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.