Pragmatic Clinical Trials for Dementia Care: Experience from the First 5 Years of the IMPACT Collaboratory.

Jill Harrison, Susan L Mitchell, Ellen P McCarthy, Vincent Mor

Abstract read

In one paragraph

Article in Generations (San Francisco, Calif.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Large language models for deductive qualitative content analysis in dementia-focused embedded pragmatic clinical trials: A comparative methodological study.Implementation science communications · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jill HarrisonNIA IMPACT Collaboratory and associate professor of the Practice at Brown University, School of Public Health in Providence, RI.

Susan L MitchellNIA IMPACT Collaboratory, a senior scientist at the Marcus Institute for Aging Research, Hebrew SeniorLife, and a professor of Medicine at Harvard Medical School in Cambridge, MA.

Ellen P McCarthyNIA IMPACT Collaboratory and an associate scientist in Palliative Care at the Hinda and Arthur Marcus Institute for Aging Research and an associate professor of Medicine at Harvard Medical School and Epidemiology at the T.H. Chan Harvard School of Public Health.

Vincent MorNIA IMPACT Collaboratory, and a professor at Brown University, School of Public Health.

Funding

Training Core (I)U54AG063546 · NIA · BROWN UNIVERSITY · PI JOSEPH E. GAUGLER · 2019 to 2026

$125.9M

NIA NIH HHS U54 AG063546

6 · The paper itself

Abstract

The IMPACT Collaboratory is a national infrastructure and resource dedicated to transforming dementia care in real-world environments for millions of Americans and their care partners, using embedded pragmatic clinical trials. This new approach of applied clinical research holds the promise of accelerating the science of dementia care, improving relevancy of interventions to real-world partners, promoting health equity, and closing the gaps between research, everyday clinical practice, and lived experiences of people living with dementia and their care partners.

Indexed as

Alzheimer’s diseasedementiapragmatic clinical trialsreal-world

Identifiers

PMID39347535

PMCPMC11429579

What OpenQuestion holds

Textmetadata

LicenceTDM

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.