Evidence map›Paper›PMID 39347246›Full record

ArticleCureus2024

Correlation of Hemoglobin, Albumin, Lymphocyte, and Platelets (HALP) Score With Outcome of Acute Ischemic Stroke.

Nithesh Babu Ramesh, Abinaya Srinivasa Rangan, Gnanadeepan Thirugnanam, Mahendra Kumar Kalappan

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nithesh Babu RameshGeneral Medicine, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Abinaya Srinivasa RanganGeneral Medicine, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Gnanadeepan ThirugnanamGeneral Medicine, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Mahendra Kumar KalappanGeneral Medicine, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute ischemic stroke (AIS) stands as a primary cause of both mortality and enduring disability. Given its significant impact on public health, efforts are ongoing to improve prognostic instruments and treatment approaches for this illness. In recent years, attention has been drawn towards the exploration of novel indicators of hemoglobin, albumin, lymphocyte, and platelets (HALP) that measure systemic inflammation and nutritional status. This study aims to investigate the relationship between the HALP score and the outcome of an acute ischemic stroke. METHODOLOGY: This prospective observational study was conducted at a tertiary care hospital, with approval from the Institutional Ethical Committee. A total of 100 AIS patients were enrolled in the study, and their demographic details were collected. Within 24 hours of stroke onset, laboratory tests were performed, including measurements of albumin, hemoglobin, lymphocytes, and platelet count. The HALP scores of these patients were recorded. The severity of AIS was assessed using the National Institutes of Health Stroke Scale (NIHSS) upon admission.

resultsThis study comprised 100 patients, with 66% and 44% being male and female, respectively, with a standard deviation of age 63. Following 28 days of in-hospital care and a 90-day outpatient follow-up, 16 patients were categorized as the non-survival group. The results showed a significant difference in hemoglobin values in the admitted groups (p = 0.04). Lymphocyte counts were higher in survivors compared to non-survivors with non-significant (p = 0.105). Furthermore, the HALP score of survivors is (a median of 34.0) and for non-survivors is (a median of 24.0), which showed a significant difference with a p-value of 0.022 and is statistically significant.  Conclusion: Lower HALP score is associated with increased mortality in stroke patients. The HALP score emerges as a potentially valuable predictor of mortality in critically ill patients. This underscores the importance of considering the HALP score in prognostic assessments and treatment decisions for individuals affected by stroke.

Indexed as

acute ischemic strokeclinical predictorsimmunohematological markersischemic stroke prognosismortalitystroke outcomestroke risk factors

Identifiers

PMID39347246
PMCPMC11427763

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.