Evidence map›Paper›PMID 39347226›Full record

ArticleCureus2024

Exploring Cotard's Delusion Within the Context of Major Depressive Disorder With Psychotic Features: A Case Report.

Alina F Faunce, William B Tennant

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alina F FaunceResearch, Alabama College of Osteopathic Medicine, Dothan, USA.
William B TennantPsychiatry, Turning Point Psychiatry, Cullman Regional Medical Center, Cullman, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cotard's delusion is a rare and complex condition marked by profound detachment from reality and nihilistic beliefs about decay and mortality, often stemming from underlying psychiatric or neurological issues. In the case of Mr. B, a 44-year-old man with a history of seizure disorder and major depressive disorder (MDD) with psychotic features, his delusions included beliefs that his right leg was decaying and that he was deceased. Despite treatment attempts with various combinations of antidepressants and antipsychotics, his delusions worsened, achieving substantial relief only through venlafaxine monotherapy. This outcome, highlighting the potential inefficacy of antipsychotics and the success of venlafaxine, underscores the need for better understanding and additional pharmacological research into Cotard's delusion, particularly within the context of MDD with psychotic features. The exact mechanism through which venlafaxine achieved a positive response remains unknown, necessitating further comprehensive studies.

Indexed as

biopsychosocial modelcotard's delusionnihilistic delusionsunipolar psychotic depressionvenlafaxine

Identifiers

PMID39347226
PMCPMC11435227

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.