Evidence map›Paper›PMID 39347164›Full record

ArticleCureus2024

Worrying Presence of Asymptomatic Bacterial Colonisation on Implanted Orthopedic Devices.

Leonardo Previ, Raffaele Iorio, Mariacarmela Solmone, Daniele Mazza, Fabio Marzilli, Riccardo Di Niccolo, Federico Corsetti, Edoardo Viglietta, Alessandro Carrozzo, Nicola Maffulli

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Peri-implant soft tissue colonization after osteosynthesis in asymptomatic patients: a prospective study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026
    Article
  2. Management of orthopedic plate exposure: a case series evaluating advanced wound care and delayed hardware removal.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Leonardo PreviOrthopedics and Traumatology, Ospedale Sant'Andrea, Rome, ITA.
Raffaele IorioOrthopedics and Traumatology, Ospedale Sant'Andrea, Rome, ITA.
Mariacarmela SolmoneMicrobiology, Ospedale Sant'Andrea, Rome, ITA.
Daniele MazzaOrthopedics and Traumatology, Ospedale Sant'Andrea, Rome, ITA.
Fabio MarzilliOrthopedics and Trauma, Ospedale Santo Spirito, Pescara, ITA.
Riccardo Di NiccoloOrthopedics and Traumatology, Ospedale Sant'Andrea, Rome, ITA.
Federico CorsettiOrthopedics and Traumatology, Ospedale Sant'Andrea, Rome, ITA.
Edoardo VigliettaOrthopedics and Traumatology, Ospedale Sant'Andrea, Rome, ITA.
Alessandro CarrozzoOrthopedics and Traumatology, Ospedale Sant'Andrea, rome, ITA.
Nicola MaffulliTrauma and Orthopaedic Surgery, University of Rome, Rome, ITA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Bacterial infection after hardware implantation in orthopedic and trauma surgery is devastating, resulting in increased hospital costs and stays, multiple revision surgeries, and prolonged use of antibiotics. The present study aims to determine whether a symbiotic relationship between the human organism and bacteria in hardware implantation may be present, without clinically evident infection. Materials and methods We studied explanted devices for microbiological analysis, using the sonication technique, from patients who underwent surgical removal of musculoskeletal hardware for mechanical reasons. None of the patients included in the study had clinical or biochemical signs of infection. Results Forty-nine patients were enrolled. Cultures tested positive for bacteria in 42.8% of the 49 patients (21 of 49). In 13 patients, Gram-positive bacteria were isolated, while Gram-negative bacteria were isolated from nine patients. The most frequent bacterial species found was

Indexed as

bacterial colonizationbiofilmmicrobiomemicrobiotaorthopedic microbiomesonication

Identifiers

PMID39347164
PMCPMC11438488

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.