Evidence map›Paper›PMID 39346999›Full record

ArticleBiomedical optics express2024

Non-invasive optical and laboratory hematologic biomarkers correlate in patients with sickle cell disease.

Timothy Quang, Golnar Mostashari, Elise Berning, Bindu Parachalil Gopalan, Maria A Lizarralde-Iragorri, Dianna Lovins, Arun S Shet, Bruce J Tromberg

Abstract read
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In one paragraph

Article in Biomedical optics express, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Timothy QuangNational Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20814, USA.
Golnar MostashariNational Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20814, USA.
Elise BerningNational Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20814, USA.
Bindu Parachalil GopalanNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20814, USA.
Maria A Lizarralde-IragorriNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20814, USA.
Dianna LovinsNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20814, USA.
Arun S ShetNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20814, USA.
Bruce J TrombergNational Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD 20814, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The goal of this study is to identify non-invasive optical hemodynamic biomarkers that can index laboratory hematology measurements in sickle cell disease (SCD). We acquired frequency-domain NIRS (FD-NIRS) and diffuse correlation spectroscopy (DCS) data from the forearms and foreheads of 17 participants in a randomized, double-blind, placebo-controlled trial evaluating effects of isoquercetin (IQ) on thromboinflammation in SCD. We observed multiple, significant correlations between optical and hematology biomarkers including cerebral tissue oxygen saturation (StO

Identifiers

PMID39346999
PMCPMC11427197

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.