Evidence map›Paper›PMID 39346987›Full record

ArticleBiomedical optics express2024

Unsupervised denoising of photoacoustic images based on the Noise2Noise network.

Yanda Cheng, Wenhan Zheng, Robert Bing, Huijuan Zhang, Chuqin Huang, Peizhou Huang, Leslie Ying, Jun Xia

Abstract read
In one paragraph

Article in Biomedical optics express, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yanda ChengDepartment of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, New York, USA.
Wenhan ZhengDepartment of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, New York, USA.
Robert BingDepartment of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, New York, USA.
Huijuan ZhangDepartment of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, New York, USA.
Chuqin HuangDepartment of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, New York, USA.
Peizhou HuangDepartment of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, New York, USA.
Leslie YingDepartment of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, New York, USA.
Jun XiaDepartment of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, New York, USA.

Funding

Development of photoacoustic tomography for non-invasive, label-free imaging of tissue perfusion in chronic woundsR01EB028978 · NIBIB · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI XIA, JUN · 2021 to 2024
$1.6M
Multiparametric photoacoustic and ultrasonic imaging of the breast in cranial-caudal viewR01EB029596 · NIBIB · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI XIA, JUN · 2020 to 2023
$1.4M
NIBIB NIH HHS R01 EB028978NIBIB NIH HHS R01 EB029596
6 · The paper itself

Abstract

In this study, we implemented an unsupervised deep learning method, the Noise2Noise network, for the improvement of linear-array-based photoacoustic (PA) imaging. Unlike supervised learning, which requires a noise-free ground truth, the Noise2Noise network can learn noise patterns from a pair of noisy images. This is particularly important for in vivo PA imaging, where the ground truth is not available. In this study, we developed a method to generate noise pairs from a single set of PA images and verified our approach through simulation and experimental studies. Our results reveal that the method can effectively remove noise, improve signal-to-noise ratio, and enhance vascular structures at deeper depths. The denoised images show clear and detailed vascular structure at different depths, providing valuable insights for preclinical research and potential clinical applications.

Identifiers

PMID39346987
PMCPMC11427216

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.