Evidence map›Paper›PMID 39346946›Full record

ArticleFrontiers in medicine2024

Genetic biomarker prediction based on gender disparity in asthma throughout machine learning.

Cai Chen, Fenglong Yuan, Xiangwei Meng, Fulai Peng, Xuekun Shao, Cheng Wang, Yang Shen, Haitao Du, Danyang Lv, Ningling Zhang and 3 more

Abstract read
In one paragraph

Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Cai Chen *Shandong Institute of Advanced Technology, Chinese Academy of Sciences, Jinan, China.
Fenglong Yuan *Department of Pulmonary and Critical Care Medicine, Yantai Yeda Hospital, Yantai, China.
Xiangwei MengBiomedical Engineering Institute, School of Control Science and Engineering, Shandong University, Jinan, China.
Fulai PengShandong Institute of Advanced Technology, Chinese Academy of Sciences, Jinan, China.
Xuekun ShaoSchool of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China.
Cheng WangShandong Academy of Chinese Medicine, Jinan, China.
Yang ShenTongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Haitao DuShandong Academy of Chinese Medicine, Jinan, China.
Danyang LvShandong Institute of Advanced Technology, Chinese Academy of Sciences, Jinan, China.
Ningling ZhangShandong Institute of Advanced Technology, Chinese Academy of Sciences, Jinan, China.
Xiuli WangDepartment of Pulmonary and Critical Care Medicine, Yantai Yeda Hospital, Yantai, China.
Tao WangNeck-Shoulder and Lumbocrural Pain Hospital of Shandong First Medical University, Jinan, China.
Ping WangShandong Academy of Chinese Medicine, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Asthma is a chronic respiratory condition affecting populations worldwide, with prevalence ranging from 1-18% across different nations. Gender differences in asthma prevalence have attracted much attention. Purpose: The aim of this study was to investigate biomarkers of gender differences in asthma prevalence based on machine learning. Method: The data came from the gene expression omnibus database (GSE69683, GSE76262, and GSE41863), which involved in a number of 575 individuals, including 240 males and 335 females. Theses samples were divided into male group and female group, respectively. Grid search and cross-validation were employed to adjust model parameters for support vector machine, random forest, decision tree and logistic regression model. Accuracy, precision, recall, and F Result: In datasets GSE76262 and GSE69683, support vector machine, random forest, logistic regression, and decision tree all achieve 100% accuracy, precision, recall, and F Conclusion: XIST serves as a genetic biomarker for gender differences in the prevalence of asthma.

Indexed as

asthmabiomarkergender disparitymachine learningprevalence

Identifiers

PMID39346946
PMCPMC11427272

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.