Evidence map›Paper›PMID 39346838›Full record

ArticleACS omega2024

Characterization of

Paloma Rezende Corrêa, Marcos Gustavo Araujo Schwarz, Deborah Antunes, Sindy Licette Piñero, Marlon Castro Silva, Mayra Mangabeira Crescêncio, Ana Carolina Ramos Guimarães, Wim Maurits Degrave, Leila Mendonça-Lima

Abstract read
In one paragraph

Article in ACS omega, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Paloma Rezende CorrêaLaboratório de Genômica Funcionale Bioinformática, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21040-900, Brazil.
Marcos Gustavo Araujo SchwarzLaboratório de Genômica Funcionale Bioinformática, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21040-900, Brazil.ORCID https://orcid.org/0000-0002-6858-0860
Deborah AntunesLaboratório de Genômica Funcionale Bioinformática, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21040-900, Brazil.ORCID https://orcid.org/0000-0002-2927-0800
Sindy Licette PiñeroLaboratório de Genômica Funcionale Bioinformática, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21040-900, Brazil.
Marlon Castro SilvaLaboratório de Genômica Funcionale Bioinformática, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21040-900, Brazil.
Mayra Mangabeira CrescêncioLaboratório de Genômica Funcionale Bioinformática, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21040-900, Brazil.
Ana Carolina Ramos GuimarãesLaboratório de Genômica Funcionale Bioinformática, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21040-900, Brazil.ORCID https://orcid.org/0000-0003-1260-543X
Wim Maurits DegraveLaboratório de Genômica Funcionale Bioinformática, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21040-900, Brazil.
Leila Mendonça-LimaLaboratório de Genômica Funcionale Bioinformática, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro 21040-900, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

l-asparaginase is an enzyme catalyzing the hydrolysis of l-asparagine into l-aspartate and ammonia, which is of great therapeutic importance in tumor treatment. However, commercially available enzymes are associated with adverse effects, and searching for a new l-asparaginase with better pharmaceutical properties was the aim of this work. The coding sequence for

Identifiers

PMID39346838
PMCPMC11425952

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.