Evidence map›Paper›PMID 39346741›Full record

ArticleFrontiers in oncology2024

Sialyl-Tn glycan epitope as a target for pancreatic cancer therapies.

Rafaela Abrantes, Joanne Lopes, Daniel Lopes, Joana Gomes, Sónia A Melo, Celso A Reis

Abstract read
In one paragraph

Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rafaela AbrantesInstituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal.
Joanne LopesDepartment of Pathology, Unidade Local de Saúde (ULS) de São João, Porto, Portugal.
Daniel LopesInstituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal.
Joana GomesInstituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal.
Sónia A MeloInstituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal.
Celso A ReisInstituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer (PC) is the sixth leading cause of cancer-related deaths worldwide, primarily due to late-stage diagnosis and limited treatment options. While novel biomarkers and immunotherapies are promising, further research into specific molecular targets is needed. Glycans, which are carbohydrate structures mainly found on cell surfaces, play crucial roles in health and disease. The Thomsen-Friedenreich-related carbohydrate antigen Sialyl-Tn (STn), a truncated

Indexed as

glycosylationpancreatic cancerSialyl-Tntargeted therapytruncated O-glycans

Identifiers

PMID39346741
PMCPMC11427427

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.