Evidence map›Paper›PMID 39346673›Full record

ArticleiScience2024

Spike transmission failures in axons from cortical neurons

Netanel Ofer, Victor Hugo Cornejo, Rafael Yuste

Abstract read
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Correlative Imaging Platform Linking Taste Cell Function to Molecular Identity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Netanel OferNeurotechnology Center, Department Biological Sciences, Columbia University, New York, NY 10027, USA.
Victor Hugo CornejoNeurotechnology Center, Department Biological Sciences, Columbia University, New York, NY 10027, USA.
Rafael YusteNeurotechnology Center, Department Biological Sciences, Columbia University, New York, NY 10027, USA.

Funding

Reexamining the Role of Dendrites in Neuronal FunctionRM1NS132981 · NINDS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Jayeeta Basu, RAFAEL YUSTE · 2023 to 2026
$10.3M
Effect of GABAergic inhibition of dendritic spines on synaptic pruning in the medial prefrontal cortex during adolescenceR01MH115900 · NIMH · SUNY DOWNSTATE MEDICAL CENTER · PI SMITH, SHERYL S · 2019 to 2023
$3.2M
Mechanisms of Neuronal Ensembles in Visual CortexR01EY035248 · NEI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI RAFAEL YUSTE · 2024 to 2026
$1.7M
NEI NIH HHS R01 EY035248NIMH NIH HHS R01 MH115900NINDS NIH HHS RM1 NS132981
6 · The paper itself

Abstract

The propagation of action potentials along axons is traditionally considered reliable due to the high safety factor for axonal spike transmission. However, numerical simulations suggest that high-frequency spikes could fail to invade distal axonal branches. To explore this experimentally

Indexed as

Cell biologyNeuroscienceSensory neuroscience

Identifiers

PMID39346673
PMCPMC11439538

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.