Evidence map›Paper›PMID 39346570›Full record

ArticleJournal of clinical medicine research2024

Physiological Stimulus for the Synthesis of Basement Membrane Proteins Leading to Its Reconstruction.

Jose Maria Pereira de Godoy, Maria de Fatima Guerreiro Godoy, Ana Carolina Pereira de Godoy, Dalisio Santi Neto

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jose Maria Pereira de GodoyCardiology and Cardiovascular Surgery Department, Medicine School in Sao Jose do Rio Preto (FAMERP), Sao Jose do Rio Preto, Brazil.ORCID https://orcid.org/0000-0001-5424-7787
Maria de Fatima Guerreiro GodoyMedicine School in Sao Jose do Rio Preto (FAMERP), Member Research Group in the Clinica Godoy, Sao Jose do Rio Preto, Brazil.ORCID https://orcid.org/0000-0003-3725-7961
Ana Carolina Pereira de GodoyIntensive Care, Pediatric Cardiology, Hospital da Crianca e Maternidade (HCM), Medicine School of Sao Jose do Rio Preto (FAMERP), Sao Jose do Rio Preto, Brazil.ORCID https://orcid.org/0000-0003-0425-4641
Dalisio Santi NetoHospital de Base, Medicine School in Sao Jose do Rio Preto (FAMERP), Sao Jose do Rio Preto, Brazil.ORCID https://orcid.org/0000-0001-8865-4313

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to report the remodeling of the basement membrane through physiological stimulus during the treatment of fibrosis in a lower limb with lymphedema. A clinical trial was conducted involving the evaluation of the basement membrane in skin biopsies before and after treatment for clinical stage II lower limb lymphedema using the Godoy method for the reversal of lymphedema and skin fibrosis. The samples were stained with Gomori's reticulin stain and evaluated using Weibel's multipoint morphometric method at the Godoy Clinic. Prior to treatment for lymphedema, rupture and important discontinuity of the basement membrane was found. After treatment, structural continuity and thickness had returned to the regions of previous rupture. The difference was statistically significant (P < 0.05, paired

Indexed as

Basement membranePhysiological stimulusSynthesis of proteins

Identifiers

PMID39346570
PMCPMC11426171

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.