Evidence map›Paper›PMID 39346507›Full record

ArticleFrontiers in psychology2024

Effects of multisession prefrontal cortex tDCS or taVNS on stress, perceived stress and sleep quality: a double-blind, randomized controlled study.

Laya Dalila Dos Reis, Laura Pereira Generoso, Gabrielly Santos Pereira, João Paulo da Silva Teixeira Barú, Natalie Lange Candido, Maria Gabriela Maziero Capello, Renato Ortolani Marcondes de Castro, Edvaldo José Rodrigues Cardoso, Robson Dias Scoz, Luciano Maia Alves Ferreira and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in psychology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07411846 (Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Perceived Stress and Psychological Distress in University Students With High Distress Levels), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07411846 nacompletednot on this mapstarted 2025, after this paper: background citation

Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Perceived Stress and Psychological Distress in University Students With High Distress Levels: A Randomized Blinded Clinical Trial

TypeinterventionalSponsorEgas Moniz - Cooperativa de Ensino Superior, CRLRan2025 to 2025Enrolled40ConditionsPsychological Distress, Stress (Psychology), Perceived StressArmstaVNS, Sham
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Laya Dalila Dos ReisLaboratory of Neuroscience, Neuromodulation and Study of Pain (LANNED), Federal University of Alfenas (UNIFAL-MG), Alfenas, Minas Gerais, Brazil.
Laura Pereira GenerosoLaboratory of Neuroscience, Neuromodulation and Study of Pain (LANNED), Federal University of Alfenas (UNIFAL-MG), Alfenas, Minas Gerais, Brazil.
Gabrielly Santos PereiraLaboratory of Neuroscience, Neuromodulation and Study of Pain (LANNED), Federal University of Alfenas (UNIFAL-MG), Alfenas, Minas Gerais, Brazil.
João Paulo da Silva Teixeira BarúLaboratory of Neuroscience, Neuromodulation and Study of Pain (LANNED), Federal University of Alfenas (UNIFAL-MG), Alfenas, Minas Gerais, Brazil.
Natalie Lange CandidoLaboratory of Neuroscience, Neuromodulation and Study of Pain (LANNED), Federal University of Alfenas (UNIFAL-MG), Alfenas, Minas Gerais, Brazil.
Maria Gabriela Maziero CapelloLaboratory of Neuroscience, Neuromodulation and Study of Pain (LANNED), Federal University of Alfenas (UNIFAL-MG), Alfenas, Minas Gerais, Brazil.
Renato Ortolani Marcondes de CastroLaboratory of Neuroscience, Neuromodulation and Study of Pain (LANNED), Federal University of Alfenas (UNIFAL-MG), Alfenas, Minas Gerais, Brazil.
Edvaldo José Rodrigues CardosoLaboratory of Neuroscience, Neuromodulation and Study of Pain (LANNED), Federal University of Alfenas (UNIFAL-MG), Alfenas, Minas Gerais, Brazil.
Robson Dias ScozNeuromodulation and Pain Unit (NeuroPain), Egas Moniz Interdisciplinary Research Center (CiiEM), Almada, Portugal.
Luciano Maia Alves FerreiraNeuromodulation and Pain Unit (NeuroPain), Egas Moniz Interdisciplinary Research Center (CiiEM), Almada, Portugal.
Marcelo Lourenço da SilvaLaboratory of Neuroscience, Neuromodulation and Study of Pain (LANNED), Federal University of Alfenas (UNIFAL-MG), Alfenas, Minas Gerais, Brazil.
Josie Resende Torres da SilvaLaboratory of Neuroscience, Neuromodulation and Study of Pain (LANNED), Federal University of Alfenas (UNIFAL-MG), Alfenas, Minas Gerais, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Chronic stress is a condition characterized by prolonged stimulation, leading to mental and physical weakness. It can have detrimental effects on individuals' mental health and cognitive function, potentially causing various health issues. This article explores the potential of non-invasive neuromodulation techniques, specifically transcranial direct current stimulation (tDCS) and transcutaneous auricular vagus nerve stimulation (taVNS), in managing chronic stress and improving sleep quality. Methods: The study conducted a randomized, double-blinded, controlled trial with participants experiencing chronic stress. In total, 100 participants were randomly assigned to one of four conditions: the anodal tDCS group ( Results: The tDCS and taVNS interventions resulted in reduced stress levels, improved sleep quality, and enhanced perception of stress. Discussion: These findings suggest that tDCS and taVNS hold promise as effective treatments for chronic stress, offering a safe and accessible approach to improving individuals' wellbeing and overall quality of life. Clinical trial registration: https://ensaiosclinicos.gov.br/rg/RBR-2ww2ts8, identifier UTN: U1111-1296-1810; Brazilian Registry of Clinical Trials (REBEC) RBR-2ww2ts8.

Indexed as

chronic stressneuromodulationsleep qualitytranscranial direct current stimulationtranscutaneous auricular vagus nerve stimulation

Identifiers

PMID39346507
PMCPMC11427356

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.