Evidence map›Paper›PMID 39346473›Full record

ArticleJournal of pharmacy & bioallied sciences2024

Investigating the Effects of Various Root Canal Irrigation Solutions on Tissue Dissolution and Microbial Control.

Ashima Jakhar, Anjali Shrivastava Vats, Simarjeev Singh, Gagandeep Thind, Nausheen Aga, Muhammad Atif Saleem Agwan, Ramanpal Singh Makkad

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Article in Journal of pharmacy & bioallied sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Ashima JakharBharati Vidyapeeth Dental College and Hospital, Navi Mumbai, Maharashtra, India.
Anjali Shrivastava VatsDepartment of Conservative Dentistry and Endodontics, Gian Sagar Dental College and Hospital, Rajpura, Patiala, Punjab, India.
Simarjeev SinghDepartment of Oral Medicine and Radiology, Gian Sagar Dental College and Hospital, Rajpura, Patiala, Punjab, India.
Gagandeep ThindDepartment of Oral Pathology and Microbiology, Gian Sagar Dental College and Hospital, Rajpura, Patiala, Punjab, India.
Nausheen AgaSchool of Dentistry, University of Dundee, DD1 4HN, Scotland, UK.
Muhammad Atif Saleem AgwanAssistant Professor, Conservative Dental Sciences Department, College of Dentistry, Qassim University, Ar-Rass, KSA.
Ramanpal Singh MakkadDepartment of Oral Medicine and Radiology, New Horizon Dental College and Research Institute, Bilaspur, Chhattisgarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Both the mechanical cleansing effect and the irrigants' capacity to disintegrate tissue are necessary for irrigation to be successful. Strong antibacterial but not poisonous to the periapical tissues and increased pulp tissue dissolution irrigant are all desirable qualities in an irrigant. Aim: To assess and compare the antibacterial properties and pulp tissue dissolving activity of various irrigation solutions. Methods and Materials: A total of 240 human mandibular permanent premolar teeth that were extracted recently for periodontal or orthodontic reasons were used in this investigation. Following irrigation, blood agar plates were used to conduct colony-forming unit (CFU) counts of the microorganism breeding colonies. Next, log CFU was computed. Before evaluating the ability of the five distinct irrigants utilized in this investigation to dissolve the frozen pulp tissues, the tissues were first smashed into smaller pieces using a mallet. Results: The bacterial count after irrigation in category 1 (normal saline), category 2 (aqueous ozone), category 3 (ethylenediaminetetraacetic acid (EDTA)), category 4 (chlorhexidine gluconate (CHX)), category 5 (super-oxidized water), and category 6 (sodium hypochlorite (NaOCl)) was 6.08 ± 0.87 log CFU mL Conclusion: NaOCl has maximum antimicrobial reduction and pulp tissue dissolution property.

Indexed as

Antimicrobial propertiesendodontic irrigantstissue dissolution

Identifiers

PMID39346473
PMCPMC11426701

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.