ArticleJournal of pharmacy & bioallied sciences2024
Effect of Fixed Orthodontic Appliances on Oral Microbial Changes and Dental Caries Risk in Children: A 6-Month Prospective Study.
Article in Journal of pharmacy & bioallied sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Effects of demineralization around orthodontic brackets bonded with different adhesive agents on fatigue-based shear bond strength: an in vitro comparative study.BMC oral health · 2026Article
- Shear Bond Strength of Orthodontic Brackets on Demineralized Enamel Before and After Application of a Resin Infiltrant Remineralizing Agent: An In Vitro Study.Dentistry journal · 2026Article
- Exploring the Link Between Mothers' Dental Health and Their Children's Cavity Status.Journal of pharmacy & bioallied sciences · 2025Article
- Daily probiotic supplementation on plaque pH and gingival health in adults: A clinical study.Bioinformation · 2025Article
- Quantitative Determination of Salivary Cariogenic Bacteria in Patients With Fixed Orthodontic Appliances.Cureus · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Orthodontic treatment can alter the oral environment, leading to plaque accumulation and changes in microbial colonization. This study aimed to assess microbiological changes in 10 to 16-year-old children undergoing fixed orthodontic treatment. Methodology: The study included children aged 10-16 years, with one group wearing fixed orthodontic appliances and a control group without brackets. Data on salivary pH, buffer capacity, Streptococcus mutans, and Lactobacillus spp were collected at baseline and after 6 months. Logistic regression models evaluated associations between orthodontic treatment and elevated bacterial levels, adjusting for age, gender, pH, and buffer capacity. Results: Wearing fixed orthodontic appliances was significantly associated with elevated Streptococcus mutans (aOR: 6.62, 95% CI: 1.91-21.88) and Lactobacillus spp (aOR: 9.49, 95% CI: 2.57-35.07). Gender showed a significant association with Lactobacillus spp levels (aOR: 0.28, 95% CI: 0.09-0.87). Conclusion: Fixed orthodontic appliances significantly impact oral microbial changes, underscoring the need for proper oral hygiene during orthodontic treatment to reduce dental caries risk.
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Registered trials
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