Evidence map›Paper›PMID 39345805›Full record

ArticleCureus2024

Expression Profiles of Claudin Gene Family Members in Patients With Recurrent Calcium Oxalate Kidney Stones.

Umit Uysal, Süleyman Sagir, Cansu Baris Mogul, Vildan Caner, O Levent Tuncay

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Umit UysalDepartment of Urology, Mardin Training and Research Hospital, Mardin, TUR.
Süleyman SagirDepartment of Urology, Mardin Artuklu University, Mardin, TUR.
Cansu Baris MogulDepartment of Medical Biology, School of Medicine, Pamukkale University, Denizli, TUR.
Vildan CanerDepartment of Medical Genetics, School of Medicine, Pamukkale University, Denizli, TUR.
O Levent TuncayDepartment of Urology, School of Medicine, Pamukkale University, Denizli, TUR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn this study, we aimed to evaluate and compare the expression profiles of

methodsNineteen patients with recurrent calcium oxalate renal calculi who underwent percutaneous nephrolithotomy and 21 control patients without renal calculi who underwent surgery for other reasons were included in the study. The urinary calcium, oxalate, and citrate levels of the patients included in the study, as well as those in the control group, were within normal ranges. They did not have proteinuria in their urine. The biochemical parameters were also within normal limits. Biopsy samples taken from the intact renal cortex parenchymal tissue were consistent. Total RNA was isolated from biopsy samples and expression profiles of target genes (

resultsIt was determined that

Indexed as

calcium oxalate stoneclaudin 1claudinsnephrolithiasisparacellular pathwayrecurrent kidney stones

Identifiers

PMID39345805
PMCPMC11436386

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.