Evidence map›Paper›PMID 39345789›Full record

ArticleJAMIA open2024

VMAP: Vaginal Microbiome Atlas during Pregnancy.

Antonio Parraga-Leo, Tomiko T Oskotsky, Boris Oskotsky, Camilla Wibrand, Alennie Roldan, Alice S Tang, Connie W Y Ha, Ronald J Wong, Samuel S Minot, Gaia Andreoletti and 14 more

Abstract read
In one paragraph

Article in JAMIA open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors.

Antonio Parraga-LeoBakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA 94143, United States.
Tomiko T OskotskyBakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA 94143, United States.
Boris OskotskyBakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA 94143, United States.
Camilla WibrandBakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA 94143, United States.
Alennie RoldanBakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA 94143, United States.
Alice S TangBakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA 94143, United States.
Connie W Y HaBenioff Center for Microbiome Medicine, Department of Medicine, University of California, San Francisco, CA 94143, United States.
Ronald J WongDepartment of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, United States.
Samuel S MinotData Core, Fred Hutchinson Cancer Center, Seattle, WA 98109, United States.ORCID https://orcid.org/0000-0003-1639-3905
Gaia AndreolettiBakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA 94143, United States.
Idit KostiBakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA 94143, United States.
Kevin R TheisDepartment of Biochemistry, Microbiology and Immunology, Wayne State University, Detroit, MI 48201, United States.
Sherrianne NgImperial College Parturition Research Group, Institute of Reproductive and Developmental Biology, Department of Metabolism, Digestion and Reproduction, Imperial College London, London W12 0NN, United Kingdom.
Yun S LeeImperial College Parturition Research Group, Institute of Reproductive and Developmental Biology, Department of Metabolism, Digestion and Reproduction, Imperial College London, London W12 0NN, United Kingdom.
Patricia Diaz-GimenoIVIRMA Global Research Alliance, IVI Foundation, Instituto de Investigación Sanitaria La Fe (IIS La Fe), Valencia 28023, Spain.ORCID https://orcid.org/0000-0003-0031-7545
Phillip R BennettImperial College Parturition Research Group, Institute of Reproductive and Developmental Biology, Department of Metabolism, Digestion and Reproduction, Imperial College London, London W12 0NN, United Kingdom.
David A MacIntyreImperial College Parturition Research Group, Institute of Reproductive and Developmental Biology, Department of Metabolism, Digestion and Reproduction, Imperial College London, London W12 0NN, United Kingdom.ORCID https://orcid.org/0000-0002-4186-5567
Susan V LynchBenioff Center for Microbiome Medicine, Department of Medicine, University of California, San Francisco, CA 94143, United States.
Roberto RomeroPregnancy Research Branch, Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892, United States.
Adi L TarcaPregnancy Research Branch, Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892, United States.
David K StevensonDepartment of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, United States.
Nima AghaeepourDepartment of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, United States.
Jonathan L GolobMarch of Dimes Prematurity Research Center at the University of California San Francisco, San Francisco, CA 94143, United States.
Marina SirotaBakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA 94143, United States.

Funding

Stanford Alzheimer's Disease Research CenterAdmin Supp: Developing iPSC models for AD and PDP30AG066515 · NIA · STANFORD UNIVERSITY · PI ELIZABETH MORMINO · 2020 to 2026
$29.0M
Preeclampsia to cardiovascular disease: Life course analysis of biomarkers and riskR01HL139844 · NHLBI · STANFORD UNIVERSITY · PI HLATKY, MARK A., WINN, VIRGINIA D · 2018 to 2021
$9.0M
SPRINT: Signature for Pain Recovery IN TeensR61NS114926 · NINDS · STANFORD UNIVERSITY · PI SIMONS, LAURA E · 2019 to 2019
$5.4M
Dietary Modulation of Neuroinflammation in Age-Related Memory DisordersR01AG058417 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SLOAN, RICHARD P, SMALL, SCOTT A · 2018 to 2022
$4.2M
Machine Learning for Integrative Modeling of the Immune System in Clinical SettingsR35GM138353 · NIGMS · STANFORD UNIVERSITY · PI AGHAEEPOUR, NIMA · 2020 to 2024
$2.2M
NHLBI NIH HHS R01 HL139844NIA NIH HHS P30 AG066515NIA NIH HHS R01 AG058417NIGMS NIH HHS R35 GM138353NINDS NIH HHS R61 NS114926
6 · The paper itself

Abstract

Objectives: To enable interactive visualization of the vaginal microbiome across the pregnancy and facilitate discovery of novel insights and generation of new hypotheses. Material and Methods: Vaginal Microbiome Atlas during Pregnancy (VMAP) was created with R shiny to generate visualizations of structured vaginal microbiome data from multiple studies. Results: VMAP (http://vmapapp.org) visualizes 3880 vaginal microbiome samples of 1402 pregnant individuals from 11 studies, aggregated via open-source tool MaLiAmPi. Visualized features include diversity measures, VALENCIA community state types, and composition (phylotypes, taxonomy) that can be filtered by various categories. Discussion: This work represents one of the largest and most geographically diverse aggregations of the vaginal microbiome in pregnancy to date and serves as a user-friendly resource to further analyze vaginal microbiome data and better understand pregnancies and associated outcomes. Conclusion: VMAP can be obtained from https://github.com/msirota/vmap.git and is currently deployed as an online app for non-R users.

Indexed as

16S rRNA sequencingbioinformaticsdata integrationmicrobiomevisualization

Identifiers

PMID39345789
PMCPMC11430916

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.