Evidence map›Paper›PMID 39345555›Full record

ArticlebioRxiv : the preprint server for biology2024

Fast-twitch myofibrils grow in proportion to Mylpf dosage in the zebrafish embryo.

Tayo E Adekeye, Emily M Teets, Emily A Tomak, Sadie L Waterman, Kailee A Sprague, Angelina White, Maddison L Coffin, Sabrina M Varga, Teresa E Easterbrooks, Sarah J Shepherd and 6 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Tayo E AdekeyeSchool of Biology and Ecology, the University of Maine, 04469, USA.
Emily M TeetsMolecular Genetics, The Ohio State University, 43210, USA.ORCID 0000-0002-0249-277X
Emily A TomakSchool of Biology and Ecology, the University of Maine, 04469, USA.
Sadie L WatermanSchool of Biology and Ecology, the University of Maine, 04469, USA.
Kailee A SpragueSchool of Biology and Ecology, the University of Maine, 04469, USA.
Angelina WhiteSchool of Biology and Ecology, the University of Maine, 04469, USA.
Maddison L CoffinSchool of Biology and Ecology, the University of Maine, 04469, USA.
Sabrina M VargaSchool of Biology and Ecology, the University of Maine, 04469, USA.
Teresa E EasterbrooksSchool of Biology and Ecology, the University of Maine, 04469, USA.ORCID 0000-0002-6360-8713
Sarah J ShepherdMolecular Genetics, The Ohio State University, 43210, USA.
Jared D AustinSchool of Biology and Ecology, the University of Maine, 04469, USA.
Dmitrii KrivorotkoSchool of Biology and Ecology, the University of Maine, 04469, USA.
Troy E HupperSchool of Biology and Ecology, the University of Maine, 04469, USA.
Joshua B KelleyMolecular and Biomedical Sciences, the University of Maine, 04469, USA.ORCID 0000-0002-5700-1173
Sharon L AmacherDepartments of Molecular Genetics and Biological Chemistry and Pharmacology, The Ohio State University, 43210, USA.ORCID 0000-0002-0640-5071
Jared C TalbotSchool of Biology and Ecology, the University of Maine, 04469, USA.

Funding

Regulation of Cellular Behavior in Response to Extracellular CuesP20GM144265 · NIGMS · UNIVERSITY OF MAINE ORONO · PI Benjamin L King · 2023 to 2026
$11.8M
Developmental regulation of oscillatory expressionR01GM117964 · NIGMS · OHIO STATE UNIVERSITY · PI AMACHER, SHARON L · 2015 to 2024
$2.6M
Targeted genome modification in zebrafish using zinc finger nucleasesR01GM088041 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI AMACHER, SHARON L · 2010 to 2012
$737k
The Role of Anillins in Gradient TrackingR15GM140409 · NIGMS · UNIVERSITY OF MAINE ORONO · PI KELLEY, JOSHUA BRIAN · 2021 to 2023
$528k
Investigating how Mylpf-regulated sarcomere formation influences limb skeletal developmentR15AR081019 · NIAMS · UNIVERSITY OF MAINE ORONO · PI TALBOT, JARED COFFIN · 2022 to 2022
$433k
NIAMS NIH HHS R15 AR081019NIGMS NIH HHS P20 GM144265NIGMS NIH HHS R01 GM088041NIGMS NIH HHS R01 GM117964NIGMS NIH HHS R15 GM140409
6 · The paper itself

Abstract

Muscle cells become stronger by expanding myofibrils, the chains of sarcomeres that produce contraction. Here we investigate how Mylpf (Myosin Light Chain Phosphorylatable Fast) abundance impacts myofibril assembly in fast-twitch muscle. The two zebrafish Mylpf genes (

Identifiers

PMID39345555
PMCPMC11429778

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.