Evidence map›Paper›PMID 39345476›Full record

ArticlebioRxiv : the preprint server for biology2024

Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis.

Romane Manceau, Danie Majeur, Celena M Cherian, Colin J Miller, Lianna W Wat, Jasper D Fisher, Audrey Labarre, Serena Hollman, Sanjana Prakash, Sébastien Audet and 26 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

36 authors.

Romane ManceauDepartments of Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.
Danie MajeurDepartments of Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.
Celena M CherianDepartment of Cellular and Physiological Sciences, The University of British Columbia, Vancouver, BC, Canada.
Colin J MillerDepartment of Cellular and Physiological Sciences, The University of British Columbia, Vancouver, BC, Canada.
Lianna W WatDepartment of Cellular and Physiological Sciences, The University of British Columbia, Vancouver, BC, Canada.
Jasper D FisherDepartment of Cellular and Physiological Sciences, The University of British Columbia, Vancouver, BC, Canada.
Audrey LabarreDepartments of Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.
Serena HollmanDepartment of Cellular and Physiological Sciences, The University of British Columbia, Vancouver, BC, Canada.
Sanjana PrakashDepartment of Cellular and Physiological Sciences, The University of British Columbia, Vancouver, BC, Canada.
Sébastien AudetDepartments of Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.
Charlotte F ChaoDepartment of Cellular and Physiological Sciences, The University of British Columbia, Vancouver, BC, Canada.
Lewis Depaauw-HoltDepartments of Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.
Benjamin RogersDepartments of Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.
Anthony BossonDepartments of Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.
Joyce J Y XiDepartment of Cellular and Physiological Sciences, The University of British Columbia, Vancouver, BC, Canada.
Catrina A S CallowDepartment of Cellular and Physiological Sciences, The University of British Columbia, Vancouver, BC, Canada.
Niyoosha YoosefiDepartment of Cellular and Physiological Sciences, The University of British Columbia, Vancouver, BC, Canada.
Niki ShahrakiDepartment of Cellular and Physiological Sciences, The University of British Columbia, Vancouver, BC, Canada.
Yi Han XiaDepartment of Cellular and Physiological Sciences, The University of British Columbia, Vancouver, BC, Canada.
Alisa HuiDepartment of Chemistry, The University of British Columbia, Vancouver, BC, Canada.
Jared VanderZwaagDivision of Medical Sciences, University of Victoria, Victoria, BC, Canada.
Khalil BouyakdanDepartments of Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.
Demetra RodarosDepartments of Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.
Pavel KotchetkovNeuroscience Program, The Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Caroline DaneaultMontreal Heart Institute Research Centre, Montreal, Canada. QC, Canada.
Ghazal FallahpourDepartment of Cellular and Physiological Sciences, The University of British Columbia, Vancouver, BC, Canada.
Martine TetreaultDepartments of Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.
Marie-Ève TremblayDivision of Medical Sciences, University of Victoria, Victoria, BC, Canada.
Matthieu RuizDepartment of Nutrition Université de Montréal, Montréal, QC, Canada.
Baptiste LacosteNeuroscience Program, The Ottawa Hospital Research Institute, Ottawa, ON, Canada.
J A ParkerDepartments of Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.ORCID 0000-0002-3333-2445
Ciaran Murphy-RoyalDepartments of Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.ORCID 0000-0001-7545-593X
Tao HuanDepartment of Chemistry, The University of British Columbia, Vancouver, BC, Canada.
Stephanie FultonDepartments of Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.
Elizabeth J RideoutDepartment of Cellular and Physiological Sciences, The University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0003-0012-2828
Thierry AlquierDepartments of Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, QC, Canada.ORCID 0000-0001-8171-802X

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI KEVIN R COOK · 2014 to 2026
$13.5M
Drosophila Transgenic RNAi Resource ProjectR01GM084947 · NIGMS · HARVARD MEDICAL SCHOOL · PI PERRIMON, NORBERT · 2008 to 2019
$9.8M
NIGMS NIH HHS R01 GM084947NIH HHS P40 OD018537
6 · The paper itself

Abstract

Lipids are essential for neuron development and physiology. Yet, the central hubs that coordinate lipid supply and demand in neurons remain unclear. Here, we combine invertebrate and vertebrate models to establish the presence and functional significance of neuronal lipid droplets (LD)

Indexed as

adipokinetic hormoneadipose triglyceride lipase (ATGL)AgRParcuate nucleusC. elegansDrosophilaenergy homeostasisLipid dropletmouseneuronsex differencetriglyceride

Identifiers

PMID39345476
PMCPMC11429983

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.