Evidence map›Paper›PMID 39345356›Full record

ArticleAIDS research and treatment2024

Relationship between Stress and Neuroimmunological Responses and Health Literacy in Newly Diagnosed HIV-Infected Patients: An Exploratory Study.

Bengt B Arnetz, Judith E Arnetz, Norbert Kaminski, Ryan Tomlin, Andrew Cole, Pamela Bartlett, Robert Crawford, Andrew Jameson

Abstract read
In one paragraph

Article in AIDS research and treatment, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bengt B ArnetzDepartment of Family Medicine Michigan State University College of Human Medicine, Grand Rapids, Michigan, USA.ORCID https://orcid.org/0000-0001-7173-4333
Judith E ArnetzDepartment of Family Medicine Michigan State University College of Human Medicine, Grand Rapids, Michigan, USA.ORCID https://orcid.org/0000-0002-0471-8701
Norbert KaminskiDepartment of Pharmacology and Toxicology Michigan State University College of Human Medicine, East Lansing, Michigan, USA.ORCID https://orcid.org/0000-0002-2144-428X
Ryan TomlinDepartment of Pharmacy Trinity Health Grand Rapids Hospital, Grand Rapids, Michigan, USA.
Andrew ColeDepartment of Family Medicine Michigan State University College of Human Medicine, Grand Rapids, Michigan, USA.
Pamela BartlettDepartment of Research & Innovation Trinity Health Grand Rapids Hospital, Grand Rapids, Michigan, USA.
Robert CrawfordInstitute for Integrative Toxicology Michigan State University, East Lansing, MI, USA.
Andrew JamesonDepartment of Medicine Trinity Health Grand Rapids Hospital, Grand Rapids, Michigan, USA.ORCID https://orcid.org/0000-0003-0017-6906

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: We aimed to study self-rated health and psycho-neuroimmunological responses during the initial 6 months after testing positive for human immunodeficiency virus (HIV) and its relationship to health literacy, that is, the ability to take in and understand information about one's illness. Health literacy plays a critical role in patients' ability to adhere to antiretroviral treatment (ART). However, there is a lack of studies on the possible impact of HIV-induced proinflammatory processes on health literacy. Methods: Twelve patients with newly diagnosed HIV attending an urban Ryan White-funded HIV clinic responded to a questionnaire and had blood samples drawn at baseline (first visit) and after 1, 3, and 6 months, respectively. The questionnaire measured stress, depression, and health literacy. Blood was analyzed for HIV RNA plasma viral load, CD4 cell count, pro- and antistress, and inflammatory markers. Results: Complete data for the entire 4 collection periods were available for nine patients. Over the 6-month period, mean viral load decreased from 353,714.83 (standard deviation 870,334.61) to 35.89 (14.04) copies/mL ( Conclusion: Both stress and proinflammatory processes in newly diagnosed HIV-infected patients might adversely impact patients' health literacy and thus their capacity to align with treatment guidance.

Identifiers

PMID39345356
PMCPMC11436276

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.