Evidence map›Paper›PMID 39345287›Full record

ArticleJournal of clinical biochemistry and nutrition2024

Plasma-activated medium exerts tumor-specific inhibitory effect on hepatocellular carcinoma via disruption of the salvage pathway.

Yu Bai, Chenwei Dai, Nini Chen, Xiuhong Zhou, Hua Li, Qinghua Xu, Yong Xu

Abstract read
In one paragraph

Article in Journal of clinical biochemistry and nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yu BaiAnhui Academy of Medical Sciences, Anhui Medical College, Gongwan Road 15, Hefei City, Anhui Province, China.
Chenwei DaiAnhui Academy of Medical Sciences, Anhui Medical College, Gongwan Road 15, Hefei City, Anhui Province, China.
Nini ChenSchool of Life Science, Anhui Agricultural University, Changjiang 130, Hefei City, Anhui Province, China.
Xiuhong ZhouAnhui Academy of Medical Sciences, Anhui Medical College, Gongwan Road 15, Hefei City, Anhui Province, China.
Hua LiSchool of Basic Medicine, Anhui Medical College, Furong Road 632, Hefei City, Anhui Province, China.
Qinghua XuAnhui Provincial Center for Disease Control and Prevention, Fanhua Road 12560, Hefei City, Anhui Province, China.
Yong XuAnhui Academy of Medical Sciences, Anhui Medical College, Gongwan Road 15, Hefei City, Anhui Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma has high fatality and poor prognosis. For curing hepatocellular carcinoma, the demand for effective therapeutic reagents with low toxicity is urgent. Herein, we investigated plasma-activated medium, an emerging reagent obtained via irradiation of cell-free medium with cold atmospheric plasma. Plasma-activated medium exerts inhibitory effect on many types of tumor cells with little toxicity to non-cancerous cells. In present study, we verified the tumor-specific inhibition of plasma-activated medium on hepatocellular carcinoma cell lines. Under the effect of plasma-activated medium, oxidative stress, mitochondrial dysfunction, and loss of intracellular NAD

Indexed as

hepatocellular carcinomaNAMPTplasma-activated mediumsalvage pathway

Identifiers

PMID39345287
PMCPMC11425076

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.