Evidence map›Paper›PMID 39345143›Full record

ArticleJournal of virology2024

Rift Valley fever virus is able to cross the human blood-brain barrier

Jordan Quellec, Camille Piro-Megy, Marion Cannac, Sébastien Nisole, Florent H Marty, Fabien Gosselet, Fumitaka Shimizu, Takashi Kanda, Catherine Cêtre-Sossah, Sara Salinas

Abstract read
In one paragraph

Article in Journal of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jordan QuellecASTRE, CIRAD, INRAE, University of Montpellier, Montpellier, France.ORCID 0000-0003-0414-0572
Camille Piro-MegyASTRE, CIRAD, INRAE, University of Montpellier, Montpellier, France.
Marion CannacIRIM, CNRS UMR9004, University of Montpellier, Montpellier, France.
Sébastien NisoleIRIM, CNRS UMR9004, University of Montpellier, Montpellier, France.
Florent H MartyPCCEI, University of Montpellier, INSERM, Etablissement Français du Sang, Montpellier, France.
Fabien GosseletBlood Brain Barrier Laboratory, Faculty of Science Jean Perrin, Artois University, Lens, France.
Fumitaka ShimizuDepartment of Neurology and Clinical Neuroscience, Yamaguchi University Graduate School of Medicine, Ube, Japan.
Takashi KandaDepartment of Neurology and Clinical Neuroscience, Yamaguchi University Graduate School of Medicine, Ube, Japan.
Catherine Cêtre-Sossah *ASTRE, CIRAD, INRAE, University of Montpellier, Montpellier, France.ORCID 0000-0002-0869-1681
Sara Salinas *PCCEI, University of Montpellier, INSERM, Etablissement Français du Sang, Montpellier, France.ORCID 0000-0003-4492-2093

Funding

Agence Nationale de la Recherche (ANR) ANR-21-CE15-0041-02Université de Montpellier (UM) KIM-RIVE
6 · The paper itself

Abstract

Rift Valley fever (RVF) is a zoonotic arboviral disease that causes recurrent epidemics in Africa that may trigger fatal neurological disorders. However, the mechanisms of neuroinvasion by which the RVF virus (RVFV) reaches the human central nervous system (CNS) remain poorly characterized. In particular, it is not clear how RVFV is able to cross the human blood-brain barrier (hBBB), which is a neurovascular endothelium that protects the brain by regulating brain and blood exchanges. To explore these mechanisms, we used an

Indexed as

AstrocytesBlood-Brain BarrierRift Valley FeverRift Valley fever virusAnimalsBrainCell LineEndothelial CellsHumansPericytesViral Nonstructural ProteinsViral Nonstructural Proteinsblood brain barrierendothelium integrityimmune responseneuroinvasionRift Valley fever virus

Identifiers

PMID39345143
PMCPMC11494904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.