Evidence map›Paper›PMID 39344996›Full record

ArticleNeurogastroenterology and motility2025

Pharmacological characterization of alpha adrenoceptor-mediated motor responses in the rat colon.

Sara Traserra, Marc Grao, Sonia Trujillo, Francesc Jiménez-Altayó, Patri Vergara, Marcel Jimenez

Abstract read
In one paragraph

Article in Neurogastroenterology and motility, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sara TraserraDepartment of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Barcelona, Spain.
Marc GraoDepartment of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Barcelona, Spain.
Sonia TrujilloDepartment of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Barcelona, Spain.
Francesc Jiménez-AltayóDepartment of Pharmacology, Universitat Autònoma de Barcelona, Barcelona, Spain.
Patri VergaraDepartment of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Barcelona, Spain.
Marcel JimenezDepartment of Cell Biology, Physiology and Immunology, Universitat Autònoma de Barcelona, Barcelona, Spain.

Funding

Agencia Estatal de Investigación
6 · The paper itself

Abstract

backgroundInhibitory neuromuscular transmission in the gastrointestinal tract is mediated by intrinsic nitrergic and purinergic neurons. Purines activate G protein-coupled receptor P2Y

methodsMuscle bath experiments were performed with the rat proximal, mid, and distal colon oriented both circularly and longitudinally.

resultsThe α

conclusionsContractile responses in the circular muscle of the mid colon could be attributed to α-adrenoceptors located on enteric cholinergic neurons. Stimulation of α

Indexed as

ColonMuscle ContractionMuscle, SmoothAdrenergic alpha-1 Receptor AgonistsAdrenergic alpha-AntagonistsAnimalsGastrointestinal MotilityMalePhenylephrineRatsRats, Sprague-DawleyRats, WistarReceptors, Adrenergic, alphaAdrenergic alpha-1 Receptor AgonistsAdrenergic alpha-AntagonistsPhenylephrineReceptors, Adrenergic, alphaalpha adrenoceptorsapamincolonphenylephrinerelaxation

Identifiers

PMID39344996
PMCPMC11650534

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.