Evidence map›Paper›PMID 39344986›Full record

ArticleToxicology and industrial health2025

Effects of bisphenol A, bisphenol S, and tetramethyl bisphenol F on male fertility in

Cole M Higley, Katelyn D Waligora, Jessica R Clore, Shannon C Timmons, Aleksandra Kuzmanov

Erratum issuedAbstract read
In one paragraph

Article in Toxicology and industrial health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. International journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Cole M HigleyDepartment of Natural Sciences, Lawrence Technological University, Southfield, MI, USA.
Katelyn D WaligoraDepartment of Natural Sciences, Lawrence Technological University, Southfield, MI, USA.
Jessica R CloreDepartment of Natural Sciences, Lawrence Technological University, Southfield, MI, USA.
Shannon C TimmonsDepartment of Natural Sciences, Lawrence Technological University, Southfield, MI, USA.ORCID 0000-0003-0178-1286
Aleksandra KuzmanovDepartment of Natural Sciences, Lawrence Technological University, Southfield, MI, USA.ORCID 0000-0003-3358-6311

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Tailoring Structures of Sulfated Oligosaccharides for Modulating Heparanase ActivityR01GM098285 · NIGMS · WAYNE STATE UNIVERSITY · PI NGUYEN, HIEN M · 2012 to 2022
$3.5M
A Search for Safer Plastics: Synthesis and Reproductive Toxicity Evaluation of Novel BisphenolsR15ES034520 · NIEHS · LAWRENCE TECHNOLOGICAL UNIVERSITY · PI KUZMANOV, ALEKSANDRA, TIMMONS, SHANNON · 2024 to 2024
$447k
NIEHS NIH HHS R15 ES034520NIGMS NIH HHS R01 GM098285NIH HHS P40 OD010440
6 · The paper itself

Abstract

Research has shown that exposure to bisphenol A (BPA), a widely used plasticizer, can lead to meiotic errors, resulting in poor reproductive cell quality and infertility. Health-related concerns have prompted the search for BPA alternatives; however, evidence suggests that currently used BPA analogs, such as bisphenol S (BPS), may pose similar risks to human health. While the effects of BPA on female fertility are well documented, the impact of BPA exposure on sperm quality is poorly understood. To better understand the effects of bisphenol analogs on spermatogenesis, we synthesized a less investigated BPA analog, tetramethyl bisphenol F (TMBPF), and compared its reprotoxic potential to that of widely used BPA and BPS using

Indexed as

Benzhydryl CompoundsCaenorhabditis elegansFertilityPhenolsSulfonesAnimalsBisphenol A CompoundsBisphenol F CompoundsBisphenol S CompoundsMaleSpermatidsSpermatogenesisSpermatozoaBenzhydryl Compoundsbisphenol ABisphenol A Compoundsbisphenol FBisphenol F Compoundsbisphenol SBisphenol S CompoundsPhenolsSulfonesBisphenol ABPA analogsC elegansmale fertilitymeiosisreprotoxicity

Identifiers

PMID39344986
PMCPMC11874479

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.