Evidence map›Paper›PMID 39344899›Full record

ArticleEpidemiology and infection2024

Combined visualization of genomic and epidemiological data for outbreaks.

Carl J E Suster, Anne E Watt, Qinning Wang, Sharon C-A Chen, Jen Kok, Vitali Sintchenko

Abstract read
In one paragraph

Article in Epidemiology and infection, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Frontiers in microbiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carl J E SusterCentre for Infectious Diseases and Microbiology - Public Health, Westmead Hospital, Westmead, NSW, Australia.ORCID 0000-0001-7021-9380
Anne E WattSydney Infectious Diseases Institute, The University of Sydney, Sydney, NSW, Australia.
Qinning WangCentre for Infectious Diseases and Microbiology - Public Health, Westmead Hospital, Westmead, NSW, Australia.
Sharon C-A ChenCentre for Infectious Diseases and Microbiology - Public Health, Westmead Hospital, Westmead, NSW, Australia.
Jen KokCentre for Infectious Diseases and Microbiology - Public Health, Westmead Hospital, Westmead, NSW, Australia.
Vitali SintchenkoCentre for Infectious Diseases and Microbiology - Public Health, Westmead Hospital, Westmead, NSW, Australia.

Funding

NSW Health Prevention Research Support Program
6 · The paper itself

Abstract

In epidemiological investigations, pathogen genomics can provide insights and test epidemiological hypotheses that would not have been possible through traditional epidemiology. Tools to synthesize genomic analysis with other types of data are a key requirement of genomic epidemiology. We propose a new 'phylepic' visualization that combines a phylogenomic tree with an epidemic curve. The combination visually links the molecular time represented in the tree to the calendar time in the epidemic curve, a correspondence that is not easily represented by existing tools. Using an example derived from a foodborne bacterial outbreak, we demonstrated that the phylepic chart communicates that what appeared to be a point-source outbreak was in fact composed of cases associated with two genetically distinct clades of bacteria. We provide an R package implementing the chart. We expect that visualizations that place genomic analyses within the epidemiological context will become increasingly important for outbreak investigations and public health surveillance of infectious diseases.

Indexed as

Disease OutbreaksGenomicsFoodborne DiseasesGenome, BacterialHumansMolecular EpidemiologyPhylogenyepidemic curvegenomic epidemiologymicrobial genomicsphylogenomicspublic healthvisualization

Identifiers

PMID39344899
PMCPMC11450504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.