Evidence map›Paper›PMID 39344714›Full record

ArticleFEBS open bio2025

Kinetic characterization of amino acid activation by aminoacyl-tRNA synthetases using radiolabelled γ-[

Igor Živković, Morana Dulic, Petra Kozulic, Marko Mocibob, Ita Gruic-Sovulj

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FEBS open bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Igor ŽivkovićDepartment of Chemistry, Faculty of Science, University of Zagreb, Zagreb, Croatia.ORCID https://orcid.org/0000-0002-6637-9530
Morana DulicDepartment of Chemistry, Faculty of Science, University of Zagreb, Zagreb, Croatia.ORCID https://orcid.org/0000-0003-2786-8996
Petra KozulicDepartment of Chemistry, Faculty of Science, University of Zagreb, Zagreb, Croatia.
Marko MocibobDepartment of Chemistry, Faculty of Science, University of Zagreb, Zagreb, Croatia.ORCID https://orcid.org/0000-0001-6537-9566
Ita Gruic-SovuljDepartment of Chemistry, Faculty of Science, University of Zagreb, Zagreb, Croatia.ORCID https://orcid.org/0000-0002-3930-8323

Funding

European Regional Development Fund KK.01.1.1.02.0016Hrvatska Zaklada za Znanost IP-2022-10-1400
6 · The paper itself

Abstract

Aminoacyl-tRNA synthetases (AARSs) are fundamental enzymes that pair amino acids and tRNAs for protein synthesis. Aminoacylation occurs in two discrete steps. The amino acid is first activated by ATP, leading to an aminoacyl-adenylate intermediate and pyrophosphate (PP

Indexed as

Adenosine TriphosphateAmino AcidsAmino Acyl-tRNA SynthetasesAminoacylationDiphosphatesKineticsRNA, TransferAdenosine TriphosphateAmino AcidsAmino Acyl-tRNA SynthetasesDiphosphatesdiphosphoric acidRNA, Transferamino acid activationaminoacyl‐tRNA synthetasesATP/PPi exchangeisotopic equilibrium exchange

Identifiers

PMID39344714
PMCPMC11961388

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.