Evidence map›Paper›PMID 39344666›Full record

ArticleJournal of the American Heart Association2024

Left Ventricular Outflow Tract Morphology as a Predictor of Conductance Disturbances Following Transcatheter Aortic Valve Replacement.

Carolina Espejo-Paeres, Luis Alfonso Marroquín-Donday, Breda Hennessey, Lin Wang, Angela McInerney, José G Paredes-Vázquez, María Pérez-Vizcayno, Gabriela Tirado-Conte, Fernando Macaya-Ten, Hernán Mejía-Rentería and 8 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Left Ventricular Outflow Tract Geometry as a Predictor of Permanent Pacemaker Implantation After Transcatheter Aortic Valve Implantation Using the Evolut Series.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Carolina Espejo-PaeresClinico San Carlos University Hospital IdISSC Madrid Spain.ORCID 0000-0002-7196-9260
Luis Alfonso Marroquín-DondayClinico San Carlos University Hospital IdISSC Madrid Spain.ORCID 0000-0002-8039-8885
Breda HennesseyClinico San Carlos University Hospital IdISSC Madrid Spain.ORCID 0000-0002-0420-943X
Lin WangClinico San Carlos University Hospital IdISSC Madrid Spain.
Angela McInerneyClinico San Carlos University Hospital IdISSC Madrid Spain.ORCID 0000-0002-1160-7735
José G Paredes-VázquezClinico San Carlos University Hospital IdISSC Madrid Spain.
María Pérez-VizcaynoClinico San Carlos University Hospital IdISSC Madrid Spain.
Gabriela Tirado-ConteClinico San Carlos University Hospital IdISSC Madrid Spain.ORCID 0000-0002-7093-3936
Fernando Macaya-TenClinico San Carlos University Hospital IdISSC Madrid Spain.
Hernán Mejía-RenteríaClinico San Carlos University Hospital IdISSC Madrid Spain.ORCID 0000-0003-1030-1926
Pablo SalinasClinico San Carlos University Hospital IdISSC Madrid Spain.ORCID 0000-0003-4040-4029
Iván Javier Núñez-GilClinico San Carlos University Hospital IdISSC Madrid Spain.ORCID 0000-0002-1779-3102
Nieves GonzaloClinico San Carlos University Hospital IdISSC Madrid Spain.ORCID 0000-0003-3827-945X
Luis Nombela-FrancoClinico San Carlos University Hospital IdISSC Madrid Spain.ORCID 0000-0003-3438-8907
Javier EscanedClinico San Carlos University Hospital IdISSC Madrid Spain.ORCID 0000-0003-4932-0112
Antonio Fernández-OrtizClinico San Carlos University Hospital IdISSC Madrid Spain.ORCID 0000-0002-3239-1910
Julián Pérez-VillacastínClinico San Carlos University Hospital IdISSC Madrid Spain.ORCID 0000-0002-4867-3912
Pilar Jiménez-QuevedoClinico San Carlos University Hospital IdISSC Madrid Spain.ORCID 0000-0001-7562-8677

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConduction disturbances represent one of the most common complications following transcatheter aortic valve replacement (TAVR). We sought to investigate the role of left ventricular outflow tract (LVOT) morphology in the development of conduction disturbances following TAVR. METHODS AND

resultsConsecutive patients who underwent TAVR in our center were included. The ratio between the LVOT area and the aortic annulus area was calculated. Patients were then divided into 2 groups on the basis of this ratio: group 1, which included patients with an LVOT area/aortic annulus area ratio <0.9; and group 2, which included patients with an LVOT area/aortic annulus area ratio ≥0.9. The primary end point was to assess the relationship between LVOT shape and the rate of permanent pacemaker implantation following TAVR. A multivariable analysis was performed to identify predictors of permanent pacemaker implantation following TAVR. From January 2018 to December 2020, 276 patients were included. Ninety-one patients with tapered LVOT morphology were assigned to group 1 and the rest (n=185 patients), tubular LVOT or flared LVOT shape, to group 2. The mean age was 81.5±5.7 years and 57% were women. After adjusting by confounding factors, tapered morphology of the LVOT and prior right bundle-branch block were found to be independent predictors of permanent pacemaker implantation (hazard ratio [HR], 2.6 [95% CI, 1.2-5.7];

conclusionsA tapered-LVOT morphology was associated with increased risk for permanent pacemaker implantation. LVOT morphology may be an additional factor to consider when choosing prosthesis size.

Indexed as

Aortic Valve StenosisTranscatheter Aortic Valve ReplacementAgedAged, 80 and overAortic ValveArrhythmias, CardiacCardiac Pacing, ArtificialFemaleHeart VentriclesHumansMalePacemaker, ArtificialPostoperative ComplicationsRetrospective StudiesRisk AssessmentRisk Factorsconduction disturbancesleft ventricular outflow tractpermanent pacemaker implantationtranscatheter aortic valve replacement

Identifiers

PMID39344666
PMCPMC11681486

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.