Evidence map›Paper›PMID 39344495›Full record

ArticleeLife2024

A promising alternative to opioids.

Jie Zhang, Jianguo Cheng

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jie ZhangDepartment of Pain Management, Cleveland Clinic, Cleveland, United States.ORCID https://orcid.org/0000-0001-9210-4154
Jianguo ChengDepartment of Pain Management, Cleveland Clinic, Cleveland, United States.ORCID https://orcid.org/0000-0002-2318-0812

Funding

A first in class, mechanism-guided, cell-based therapy for complex regional pain syndromeUG3NS127258 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI CHENG, JIANGUO · 2022 to 2022
$2.0M
NINDS NIH HHS UG3 NS127258
6 · The paper itself

Abstract

A complex extracted from the amniotic membrane in humans reduces post-surgical pain in mice by directly inhibiting pain-sensing neurons.

Indexed as

Analgesics, OpioidPostoperative PainAmnionAnimalsHumansMiceNeuronsAnalgesics, Opioidamniotic membraneclarix FLOHC-HA/PTX3medicinemouseneuroscienceopioidsPost-surgical pain

Identifiers

PMID39344495
PMCPMC11441975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.