ArticleThe Journal of organic chemistry2024
Water as a Reactant: DABCO-Catalyzed Hydration of Activated Alkynes for the Synthesis of Divinyl Ethers.
Article in The Journal of organic chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Investigating the hydrolysis-condensation of dichloromethylsilane: a simplified protocol for polymethylhydrosiloxane synthesis as a candidate for vitreous substitute.BMC chemistry · 2026Article
- Catalytic Hydrophosphorylation of Propiolates and Three-Component Phosphorylation of Aldehydes.The Journal of organic chemistry · 2026Article
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Authors and funding
5 authors.
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Abstract
A practical and efficient addition of water to readily available activated alkynes delivering divinyl ethers is reported. The reaction proceeds with full atom economy in a very straightforward experimental procedure. Additionally, of all the tertiary amines studied to catalyze the reaction, the best and most efficient is clearly DABCO (1,4-diazabicyclo[2.2.2]octane). Finally, the solvent choice is crucial for the efficiency of this process and we have found that the reaction is best performed in wet dichloromethane for propiolic esters and alkynones, and in wet acetonitrile for propiolamides.
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