Evidence map›Paper›PMID 39344297›Full record

ArticleMagnetic resonance in medicine2025

3D quantitative myocardial perfusion imaging with hyperpolarized HP001(bis-1,1-(hydroxymethyl)-[1-

Yupeng Zhao, Rie Beck Olin, Esben Søvsø Szocska Hansen, Christoffer Laustsen, Lars G Hanson, Jan Henrik Ardenkjær-Larsen

Abstract read
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In one paragraph

Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yupeng ZhaoDepartment of Health Technology, Technical University of Denmark, Kgs. Lyngby, Denmark.ORCID 0000-0002-3736-7063
Rie Beck OlinDepartment of Health Technology, Technical University of Denmark, Kgs. Lyngby, Denmark.ORCID 0000-0003-1718-8196
Esben Søvsø Szocska HansenMR Research Centre, Aarhus University, Aarhus, Denmark.ORCID 0000-0001-5512-9870
Christoffer LaustsenMR Research Centre, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-0317-2911
Lars G HansonDepartment of Health Technology, Technical University of Denmark, Kgs. Lyngby, Denmark.ORCID 0000-0002-8204-6912
Jan Henrik Ardenkjær-LarsenDepartment of Health Technology, Technical University of Denmark, Kgs. Lyngby, Denmark.ORCID 0000-0001-6167-6926

Funding

The European Union's Horizon 2020 Research and Innovation Program 858149
6 · The paper itself

Abstract

purposeThis study aims to show the viability of conducting three-dimensional (3D) myocardial perfusion quantification covering the entire heart using both GRE and bSSFP sequences with hyperpolarized HP001.

methodsA GRE sequence and a bSSFP sequence, both with a stack-of-spirals readout, were designed and applied to three pigs. The images were reconstructed using

resultsPerfusion values, estimated by both DCE and

conclusionThis study demonstrated the feasibility of 3D whole-heart myocardial perfusion quantification using hyperpolarized HP001 with both GRE and bSSFP sequences. The

Indexed as

Imaging, Three-DimensionalMyocardial Perfusion ImagingPhantoms, ImagingAlgorithmsAnimalsCarbon IsotopesContrast MediaHeartImage Processing, Computer-AssistedMagnetic Resonance ImagingSwineCarbon IsotopesContrast Mediabalanced SSFPgradient echohyperpolarized HP001MRIquantitative myocardial perfusion imaging

Identifiers

PMID39344297
PMCPMC11604847

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.