Evidence map›Paper›PMID 39344070›Full record

ReviewTherapeutic advances in respiratory disease

Bronchial thermoplasty for severe asthma: potential mechanisms and response markers.

Li ChunXiao, Hou Xin, Li Yun, Liu BoWen, Shen KunLu, Lin JiangTao

Abstract readReview
In one paragraph

Review in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Li ChunXiaoPeking University China‑Japan Friendship School of Clinical Medicine, Beijing, China.ORCID 0000-0002-5381-8442
Hou XinPeking University China‑Japan Friendship School of Clinical Medicine, Beijing, China.
Li YunGraduate School, Beijing University of Chinese Medicine, Beijing, China.
Liu BoWenGraduate School, Beijing University of Chinese Medicine, Beijing, China.
Shen KunLuGraduate School of Peking Union Medical College, Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing, China.
Lin JiangTaoNational Center for Respiratory Medicine, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, No. 2, East Yinghua Road, Chaoyang District, Beijing 100029, China.ORCID 0000-0002-0228-572X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe asthma (SA) poses a significant challenge to management and treatment, leading to a reduced quality of life and a heavy burden on society and healthcare resources. Bronchial thermoplasty (BT) has emerged as a non-pharmacological intervention for SA, demonstrating its efficacy and safety in improving patients' quality of life and reducing exacerbation rates for over a decade. In particular, BT encounters various obstacles in its clinical application. Since asthma is characterized by high heterogeneity, not all patients derive effective outcomes from BT. Furthermore, current knowledge of markers that indicate response to BT remains limited. Recent research has shed light on the intricate mechanism of action of BT, which extends beyond simple smooth muscle ablation. Therefore, to enhance the clinical practice and implementation of BT, this paper aims to elucidate the mechanism of action and identify potential markers associated with BT response.

Indexed as

AsthmaBronchial ThermoplastyQuality of LifeSeverity of Illness IndexAnimalsBiomarkersBronchiHumansLungTreatment OutcomeBiomarkersbiomarkerbronchial thermoplastymechanismsevere asthma

Identifiers

PMID39344070
PMCPMC11440556

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.