ArticleInfectious diseases of poverty2024
Further analysis of tuberculosis in eight high-burden countries based on the Global Burden of Disease Study 2021 data.
Article in Infectious diseases of poverty, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The disease burden of ILD at the global, regional, and national levels from 1990 to 2021, and projections until 2035: the 2021 Global Burden of Disease study.Frontiers in medicine · 2025Pooled it
- Tuberculosis in Cirrhosis: A Diagnostic and Therapeutic Challenge.Digestive diseases and sciences · 2026Review
- Pediatric Tuberculosis in North Kivu: The Urgency of a Targeted Response to a Forgotten Childhood Disease.Public health challenges · 2026Review
- Trends and cross-country inequalities in the global burden of thyroid cancer, 1990-2021: A population-based study.Medicine · 2026Article
- Advanced statistical approaches in tuberculosis diagnosis and treatment outcomes in Africa: a systematic review.Tropical medicine and health · 2026Review
- Community-based chest X-ray screening versus symptom-based case presentation in the elderly: evidence from three consecutive years of data.BMC geriatrics · 2026Article
- Adverse effects of linezolid in the treatment of drug-resistant tuberculosis: a scoping review.Breathe (Sheffield, England) · 2026Review
- [Active Oxygen Influences Foam Macrophage Formation by Regulating Peroxisome Proliferator-Activated Receptor-γ Expression].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026Article
- Clinical epidemiology and risk prediction of unsuccessful treatment outcomes in pulmonary tuberculosis with diabetes mellitus.BMC medicine · 2026Article
- Tuberculosis incidence and mortality trends in mainland China, 2004-2024: control program and elimination progress.Tropical medicine and health · 2026Article
- Evaluation of TST/C-TST combination for latent tuberculosis infection screening: diagnostic performance and cost-effectiveness compared to TST/IGRAs.BMC infectious diseases · 2026Article
- Trends and spatial distribution of pulmonary tuberculosis in China: a surveillance study.Frontiers in public health · 2026Article
- Article
- Identification of Misdiagnosis Factors in Allergic Bronchopulmonary Mycosis Using Explainable Machine Learning.Journal of asthma and allergy · 2026Article
- Cox Proportional Hazards Model Analysis of Survival Among Tuberculosis Patients Under Treatment in Mbuji-Mayi, Democratic Republic of the Congo.Journal of multidisciplinary healthcare · 2026Article
- A hospital-based genomic analysis reveals predominance of ST215Frontiers in microbiology · 2026Article
- Global burden and cross-country inequalities in rabies from 1990 to 2021: a systemic analysis of the global burden of disease study 2021.BMC infectious diseases · 2025Article
- Spatio-temporal trends, distribution and prediction of tuberculosis incidence in Uganda (2020-2025).BMC infectious diseases · 2025Article
- Global excess tuberculosis mortality during COVID-19: a country-level modeling study of policy and development correlates.BMC public health · 2025Article
- Analyzing factors affecting tuberculosis incidence in various mainland Chinese economic regions and predicting trends: a comprehensive regression study.BMC public health · 2025Article
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Abstract
backgroundsMost significant findings from the Global Tuberculosis (TB) Report 2023 indicate that India, Indonesia, China, the Philippines, Pakistan, Nigeria, Bangladesh, and the Democratic Republic of the Congo (DRC) collectively contribute to approximately two-thirds of global TB cases. This study aims to provide crucial data-driven insights and references to improve TB control measures through a comprehensive analysis of these eight high-burden countries.
methodsThe eight high-burden TB countries analyzed in this study include India, Indonesia, China, the Philippines, Pakistan, Nigeria, Bangladesh, and the DRC. Age-standardized incidence rates (ASIR) of TB were derived from the Global Burden of Diseases Study 2021 data. Temporal trends were analyzed using Joinpoint regression. An age-period-cohort model was applied to examine the risk ratios (RR) of TB across diverse age groups, periods, and birth cohorts. A Bayesian age-period-cohort framework was employed to predict the ASIR of TB by 2030.
resultsThe study found that the Philippines (average annual percentage change = 3.1%, P < 0.001) exhibited an upward trend from 1990 to 2021. In India, the Philippines, Pakistan, and Bangladesh, the RR of TB incidence exceeded 1 after individuals reached 25 years old. Notably, the RR has shown a consistent upward trend since 2001, peaking during the period of 2017-2021 with an estimated RR of 1.5 (P < 0.001) in the Philippines. Similarly, the highest RR was observed during the period of 2017-2021 reaching 1.1 (P < 0.001) in the DRC. In the Philippines, the markedly increasing RR values for TB have been observed among individuals born after 1997-2001. Projections suggest that the ASIR of TB is expected to follow a continued upward trajectory, with an estimated rate of 392.9 per 100,000 by 2030 in the Philippines; India and Indonesia are projected to achieve less than 20.0% of the target set by the World Health Organization (WHO).
conclusionsAmong the eight high-burden countries, the Philippines, India and Indonesia are diverging from the goals set by the WHO, and the risk of TB in the Philippines and the DRC shows a trend toward affecting younger populations, which suggests that the management strategies for TB patients need to be further strengthened.
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