Evidence map›Paper›PMID 39343491›Full record

ReviewPediatric clinics of North America2024

Overview of Pediatric Obesity as a Disease.

Stephanie W Waldrop, Awab Ali Ibrahim, Jacqueline Maya, Carmen Monthe-Dreze, Fatima Cody Stanford

Abstract readReview
In one paragraph

Review in Pediatric clinics of North America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stephanie W WaldropSection on Nutrition, Department of Pediatrics, Anschutz Medical Campus, Nutrition Obesity Research Center (NORC), University of Colorado, Aurora, CO, USA. Electronic address: stephanie.waldrop@cuanschutz.edu.
Awab Ali IbrahimDepartment of Pediatrics, Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.
Jacqueline MayaDepartment of Pediatrics, Division of Pediatric Endocrinology, MGH Weight Center, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02115, USA.
Carmen Monthe-DrezeDivision of Newborn Medicine, Department of Pediatrics, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
Fatima Cody StanfordDivision of Endocrinology-Neuroendocrine, Department of Medicine, Massachusetts General Hospital, MGH Weight Center, 50 Staniford Street, Suite 430, Boston, MA 02115, USA; Department of Pediatrics, Division of Endocrinology, Nutrition Obesity Research Center at Harvard (NORCH), Boston, MA, USA. Electronic address: https://twitter.com/askdrfatima.

Funding

ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Elizabeth Austen Lawson, Takara Leah Stanley · 1994 to 2026
$31.6M
TRAINING PROGRAM IN ENDOCRINOLOGY AND DIABETEST32DK007028 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Karen K Miller · 1986 to 2026
$18.5M
NIDDK National Research Service Award (NRSA) T32 Diversity Administrative SupplementT32DK007658 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Kristen Elizabeth Boyle, Ihuoma U Eneli · 1991 to 2026
$6.0M
Creating Opportunities for Unparalleled Researchers to Achieve Growth and Excellence (COURAGE)U24DK132733 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI MORONE, NATALIA E., STANFORD, FATIMA CODY · 2022 to 2025
$3.3M
Accelerating Research Advancement for Investigators Underrepresented in AcademiaUE5DK137285 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Fatima Cody Stanford, Takara Leah Stanley · 2023 to 2026
$621k
NIDDK NIH HHS P30 DK040561NIDDK NIH HHS T32 DK007028NIDDK NIH HHS T32 DK007658NIDDK NIH HHS U24 DK132733NIDDK NIH HHS UE5 DK137285
6 · The paper itself

Abstract

The authors highlight well-known and hypothesized pathophysiologic mechanistic links underlying obesity and the various pediatric disorders across multiple organ systems with which it is associated. Obesity is attributed to an imbalance in energy intake versus expenditure; there is growing knowledge regarding its multifactorial origins, dysfunctional physiologic processes, and adverse health consequences. Individuals with obesity exhibit variations in metabolic rate, genetic predisposition, and hormonal regulation, influencing diverse responses in regulating energy balance. Understanding the complex mechanistic relationships surrounding the pathophysiology of obesity assists in its consideration as a disease process, allowing pediatric health practitioners to manage its sequelae more effectively.

Indexed as

Pediatric ObesityChildEnergy IntakeEnergy MetabolismHumansInflammationMetabolic dysfunctionPathophysiologyPediatric obesity

Identifiers

PMID39343491
PMCPMC11443063

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.