Evidence map›Paper›PMID 39342520›Full record

ArticleWiener klinische Wochenschrift2025

Integrating palliative care into multiple myeloma management : Optimizing quality of life across the disease continuum.

Lina Rüsing, Christina Brunbauer, Clara Sophie Michel, Claudia Wenzel, Philipp Bauer, Lea Vospernik, Julia Rabensteiner, Feroniki Adamidis, Joachim Baer, Franziska Ecker and 4 more

Abstract read
In one paragraph

Article in Wiener klinische Wochenschrift, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Lina RüsingDepartment of Medicine I, Division Hematology and Hemostaseology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Christina BrunbauerDepartment of Medicine I, Division Hematology and Hemostaseology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Clara Sophie MichelDepartment of Medicine I, Division Hematology and Hemostaseology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Claudia WenzelDepartment of Medicine I, Division of Palliative Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Philipp BauerDepartment of Medicine I, Division of Palliative Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Lea VospernikDepartment of Medicine I, Division Hematology and Hemostaseology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Julia RabensteinerDepartment of Medicine I, Division of Palliative Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Feroniki AdamidisDepartment of Medicine I, Division of Palliative Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Joachim BaerDepartment of Medicine I, Division of Palliative Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Franziska EckerDepartment of Medicine I, Division of Palliative Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Lea KumDepartment of Medicine I, Division of Palliative Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Hermine AgisDepartment of Medicine I, Division Hematology and Hemostaseology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Eva Katharina MaselDepartment of Medicine I, Division of Palliative Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria. eva.masel@meduniwien.ac.at.ORCID http://orcid.org/0000-0001-6415-4488
Maria Theresa KrauthDepartment of Medicine I, Division Hematology and Hemostaseology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultiple myeloma (MM) poses significant challenges due to its complex symptomatology and evolving treatment landscape. While therapeutic advances have improved survival outcomes, holistic management of MM requires addressing the numerous physical and psychosocial needs of patients. Palliative care (PC) offers a comprehensive approach to symptom management and supportive care on a physical, psychosocial and spiritual level; however, its role in MM remains underexplored.

methodsThis retrospective single-center study examines the outcome of 22 MM patients admitted to the Division of Palliative Medicine at the Medical University of Vienna. We investigated reasons for admission, symptom severity, functional status, length of stay and overall survival.

resultsMost common reasons for palliative care unit (PCU) admission were nutritional problems (82%), fatigue (77%) and pain (68%). Median ECOG score at PCU admission was 3. The timepoint within the timeline of myeloma disease at which hospitalization took place varied greatly. Some patients were hospitalized shortly after diagnosis, other patients after many years of active disease and therapy. Median time from MM initial diagnosis to first PCU stay was 4.3 years (range 0.6-23.8 years). The median length of hospital (PCU) stay was 11 days (range 1-127days) and 45% of patients died during PCU hospitalization. The reduction in symptom burden as a result of the inpatient stay in the PCU is reflected in the PERS

conclusionPC interventions effectively addressed the complex symptom burden experienced by patients with MM. Multidimensional approaches encompassing physical, psychological and social domains proved instrumental in optimizing quality of life. Integrating PC principles into MM management paradigms is essential to prioritize patient-centered care across the disease continuum.

Indexed as

Multiple MyelomaPalliative CareQuality of LifeAdultAgedAged, 80 and overAustriaDelivery of Health Care, IntegratedFemaleHumansLength of StayMaleMiddle AgedRetrospective StudiesSurvival RateTreatment OutcomeEarly palliative careMultiple myelomaPainPalliative careSymptoms

Identifiers

PMID39342520
PMCPMC12176925

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.