Evidence map›Paper›PMID 39342387›Full record

ArticleEuropean journal of medical research2024

Biphasic effects of single-dose intravenous injection of uridine adenosine tetraphosphate on blood pressure in mice.

Yue Ma, Chen-Yang An, Xin-Xin Wang, Lu Gan, Lu Li, Kui-Hua Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yue Ma *Department of Anesthesiology, Affiliated Hospital of Hebei University, No. 212, Yuhua East Road, Lianchi District, Baoding, 071000, China.
Chen-Yang An *Department of Anesthesiology, Affiliated Hospital of Hebei University, No. 212, Yuhua East Road, Lianchi District, Baoding, 071000, China.
Xin-Xin WangDepartment of Anesthesiology, Affiliated Hospital of Hebei University, No. 212, Yuhua East Road, Lianchi District, Baoding, 071000, China.
Lu GanDepartment of Anesthesiology, Affiliated Hospital of Hebei University, No. 212, Yuhua East Road, Lianchi District, Baoding, 071000, China.
Lu LiDepartment of Anesthesiology, Affiliated Hospital of Hebei University, No. 212, Yuhua East Road, Lianchi District, Baoding, 071000, China. luli_sea@163.com.
Kui-Hua LiDepartment of Biomedical Engineering, Chengde Medical College, Anyuan Road, Shuangqiao District, Chengde, 067000, China. likuihualkh@126.com.

Funding

Key Programs of Medical Science in Hebei Province 20211165Key Scientific Research Foundation of Affiliated Hospital of Hebei University 2022ZB03Medical Science Foundation of Hebei University 2023X04
6 · The paper itself

Abstract

purposeTo explore the effects of a single dose of uridine adenosine tetraphosphate (Up

methodsThe mice were separated into three groups: the Up

resultsMice in these groups experienced a rapid increase in blood pressure, reaching its peak within 10 s after drug administration. It took approximately 120 s for the blood pressure to return to baseline levels after the administration of the drugs in both the NA and α, β-meATP groups. After higher doses of Up

conclusionCompared to NA and α, β-meATP, Up

Indexed as

Blood PressureDinucleoside PhosphatesAdenosine TriphosphateAnimalsDose-Response Relationship, DrugInjections, IntravenousMaleMiceNorepinephrineAdenosine Triphosphatealpha,beta-methyleneadenosine 5'-triphosphateDinucleoside PhosphatesNorepinephrineuridine adenosine tetraphosphateArterial blood pressureNorepinephrine (NA)Uridine adenosine tetraphosphate (Up4A)α, β-methylene adenosine triphosphate (α, β-meATP)

Identifiers

PMID39342387
PMCPMC11438126

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.