Evidence map›Paper›PMID 39342075›Full record

ArticleEuropean geriatric medicine2024

The hazard of mortality across different levels of frailty are increased among patients with high Braden scores.

Hanne Nygaard, Rikke S Kamper, Finn E Nielsen, Sofie K Hansen, Pernille Hansen, Miriam R Wejse, Eckart Pressel, Jens Rasmussen, Charlotte Suetta, Anette Ekmann

Abstract read
In one paragraph

Article in European geriatric medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hanne NygaardDepartment of Emergency Medicine, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark. hanne.nygaard@regionh.dk.ORCID 0000-0001-8609-8755
Rikke S KamperCopenAge, Copenhagen Center for Clinical Age Research, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-1927-9078
Finn E NielsenDepartment of Emergency Medicine, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark.ORCID 0000-0002-7650-6927
Sofie K HansenCopenAge, Copenhagen Center for Clinical Age Research, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-0594-3553
Pernille HansenCopenAge, Copenhagen Center for Clinical Age Research, University of Copenhagen, Copenhagen, Denmark.ORCID 0009-0004-5545-1105
Miriam R WejseCopenAge, Copenhagen Center for Clinical Age Research, University of Copenhagen, Copenhagen, Denmark.
Eckart PresselDepartment of Geriatric & Palliative Medicine, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Jens RasmussenDepartment of Emergency Medicine, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Charlotte SuettaCopenAge, Copenhagen Center for Clinical Age Research, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-8063-6508
Anette EkmannCopenAge, Copenhagen Center for Clinical Age Research, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-9890-4707

Funding

Novo Nordisk Fonden NNF18OC0052826
6 · The paper itself

Abstract

purposeTo examine the prognostic accuracy of the Clinical Frailty Scale (CFS) and Braden Scale (BS) separately and combined for 90-day mortality. Furthermore, to examine the effect of frailty on mortality depending on different levels of the Braden score.

methodsThe study included acutely admitted medical patients ≥ 65 years. We used an optimum cutoff for CSF and BS at ≥ 4 and ≤ 19, respectively. CFS categorized frailty as Non-frail (< 4), Frail (4-5), and Severely frail (> 5). Prognostic accuracy was estimated by the area under the receiver operating characteristic curves (AUROC) with 95% confidence intervals (CI). Cox regression analysis was used to compute the adjusted hazard ratio (aHR) for mortality.

resultsThe mean age among 901 patients (54% female) was 79 years. The AUROC for CFS and BS was 0.65 (CI95% 0.60-0.71) and 0.71 (CI95% 0.66-0.76), respectively. aHR for mortality of CFS ≥ 4, BS ≤ 19, and combined were 2.3 (CI95% 1.2-4.2), 1.9 (CI95% 1.3-2.9), and 1.9 (CI95% 1.3-2.8), respectively. For BS > 19, the aHR for mortality was 2.2 (CI95% 1.0-4.8) and 3.5 (CI95% 1.4-8.6) for 'frail' and 'severely frail', respectively. aHR for BS ≤ 19 was 1.1 (CI95% 0.4-3.2) and 1.3 (CI95% 0.5-3.7) for 'frail' and 'severely frail', respectively.

conclusionAlthough CFS and BS were associated with 90-day mortality among older acutely admitted medical patients, the prognostic accuracy was poor-to-moderate, and the combination of CFS and BS did not improve the prognostic accuracy. However, the hazard of mortality across different levels of frailty groups were particularly increased among patients with high BS scores.

Indexed as

Frail ElderlyFrailtyGeriatric AssessmentAgedAged, 80 and overFemaleHumansMalePrognosisProportional Hazards ModelsRisk AssessmentROC CurveSeverity of Illness IndexBraden ScaleClinical Frailty ScaleClinical researchFrailtyMortalityOld age

Identifiers

PMID39342075
PMCPMC11632018

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.