Evidence map›Paper›PMID 39340621›Full record

ArticleBulletin of experimental biology and medicine2024

Ototoxic Effect of Nicotinamide Riboside.

S A Ivanov, E Yu Podyacheva, S G Zhuravskii, Ya G Toropova

Abstract read
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

S A IvanovAlmazov National Medical Research Centre, Ministry of Health of the Russian Federation, St. Petersburg, , Russian Federation, Russia.
E Yu PodyachevaAlmazov National Medical Research Centre, Ministry of Health of the Russian Federation, St. Petersburg, , Russian Federation, Russia. ekaterinapodyachevaspb@gmail.com.
S G ZhuravskiiAlmazov National Medical Research Centre, Ministry of Health of the Russian Federation, St. Petersburg, , Russian Federation, Russia.
Ya G ToropovaAlmazov National Medical Research Centre, Ministry of Health of the Russian Federation, St. Petersburg, , Russian Federation, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied the function of the auditory system in Wistar rats after repeated intravenous administration of nicotinamide riboside (NR). The functional activity of the receptor and retrocochlear parts of the auditory system were assessed by recording short-latency auditory evoked potentials (SLAEPs) and distortion-product otoacoustic emissions (DPOAEs) at baseline, immediately after NR administration, and 1 and 2 months later. Repeated intravenous NR administration (cumulative dose of 2700 mg/kg) to Wistar rats has a detrimental impact on the structures within the cochlear section of the auditory system.

Indexed as

NiacinamidePyridinium CompoundsRats, WistarAnimalsCochleaEvoked Potentials, AuditoryMaleOtoacoustic Emissions, SpontaneousRatsNiacinamidenicotinamide-beta-ribosidePyridinium Compoundsintravenous administrationNAD+nicotinamide ribosideototoxicityside effects

Identifiers

PMID39340621

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.