Evidence map›Paper›PMID 39340611›Full record

ArticleAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2025

Dynamic extraction of residual solvents from pharmaceutical formulations using a needle-type extraction device.

Ikuo Ueta, Daisuke Kondo, Suguru Masuda, Yuki Ariizumi, Ryosuke Kikuchi, Koki Nakagami, Yoshihiro Saito

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Sample pretreatment approaches for improving versatility and convenience in gas chromatographic analysis.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ikuo UetaDepartment of Applied Chemistry, University of Yamanashi, 4-3-11 Takeda, Kofu, 400-8511, Japan. iueta@yamanashi.ac.jp.ORCID http://orcid.org/0000-0003-3991-5139
Daisuke KondoDepartment of Applied Chemistry, University of Yamanashi, 4-3-11 Takeda, Kofu, 400-8511, Japan.
Suguru MasudaDepartment of Applied Chemistry, University of Yamanashi, 4-3-11 Takeda, Kofu, 400-8511, Japan.
Yuki AriizumiDepartment of Applied Chemistry, University of Yamanashi, 4-3-11 Takeda, Kofu, 400-8511, Japan.
Ryosuke KikuchiDepartment of Pharmacy, University of Yamanashi Hospital, 1110 Shimokato, Chuo, 409-3898, Japan.
Koki NakagamiDepartment of Applied Chemistry and Life Science, Toyohashi University of Technology, 1-1 Hibarigaoka, Tempaku, Toyohashi, 441-8580, Japan.
Yoshihiro SaitoDepartment of Applied Chemistry and Life Science, Toyohashi University of Technology, 1-1 Hibarigaoka, Tempaku, Toyohashi, 441-8580, Japan.

Funding

Japan Society for the Promotion of Science 21K06491Japan Society for the Promotion of Science 24K08476Japan Society for the Promotion of Science 24K08479
6 · The paper itself

Abstract

This study developed a rapid screening method to determine residual solvents contained in a tablet formulation using a needle-type extraction device. For this, the tablet formulation was pulverized and the powdered sample was rapidly inserted into a pipette tip. After fixing the sample with quartz wool, the pipette tip was capped with a silicon septum. A needle-type extraction device packed with Carbopack X and a carbon molecular sieve was inserted into the pipette tip through the septum, and the gas sample was collected. During this gas sampling, pure N

Indexed as

NeedlesSolventsChromatography, GasPharmaceutical PreparationsTabletsPharmaceutical PreparationsSolventsTabletsGas chromatographyNeedle-type extraction deviceResidual solventsVOCs

Identifiers

PMID39340611

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.