Evidence map›Paper›PMID 39340288›Full record

ArticleAnnals of medicine2024

Analysis of the implication of steroid 5 alpha-reductase 3 on prognosis and immune microenvironment in Liver Hepatocellular Carcinoma.

Yuming Lu, Ziwei Liu, Yu Zheng, Xuesong Liu, XiaoQin Liu, Nanguan Chen, Kai Mao, Weida Lin

Abstract read
In one paragraph

Article in Annals of medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuming LuDepartment of Biostatistics, College of Science, City University of Hong Kong, Hong Kong, China.ORCID 0009-0007-6527-0465
Ziwei LiuSchool of Nursing, Guangzhou Medical University, Guangzhou, Guangdong, China.
Yu ZhengDepartment of Hepatobiliary Pancreatic Surgery, ShenShan Medical Center, Memorial Hospital of Sun Yat-Sen University, Shanwei, Guangdong, China.
Xuesong LiuDepartment of Immunology, BinZhou Medical University, Binzhou, Shandong, China.
XiaoQin LiuDepartment of Hepatobiliary Pancreatic Surgery, ShenShan Medical Center, Memorial Hospital of Sun Yat-Sen University, Shanwei, Guangdong, China.
Nanguan ChenLuoding Hospital of Traditional Chinese Medicine, Luoding, Guangdong, China.
Kai MaoDepartment of Hepatobiliary Pancreatic Surgery, ShenShan Medical Center, Memorial Hospital of Sun Yat-Sen University, Shanwei, Guangdong, China.
Weida LinDepartment of Hepatobiliary Pancreatic Surgery, ShenShan Medical Center, Memorial Hospital of Sun Yat-Sen University, Shanwei, Guangdong, China.ORCID 0009-0002-3827-013X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study combined the bioinformatics and

methodGene expression and clinical data were obtained from public databases. The prognosis was evaluated using survival, multifactor Cox, enrichment, and mutation analyses. This was then verified through

resultsThe expression level of

conclusions

Indexed as

3-Oxo-5-alpha-Steroid 4-DehydrogenaseCarcinoma, HepatocellularLiver NeoplasmsTumor MicroenvironmentBiomarkers, TumorCell Line, TumorCell ProliferationFemaleGene Expression Regulation, NeoplasticHumansKaplan-Meier EstimateMaleMembrane ProteinsMiddle AgedPrognosis3-Oxo-5-alpha-Steroid 4-DehydrogenaseBiomarkers, TumorMembrane ProteinsSRD5A3 protein, humanimmunotherapyLiver Hepatocellular Carcinomaprognosissingle cell sequencingSteroid 5 alpha-reductase 3

Identifiers

PMID39340288
PMCPMC11441025

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.