Evidence map›Paper›PMID 39340253›Full record

ArticleThe Journal of international medical research2024

Efficacy and safety of tranexamic acid use in elderly patients undergoing anterior cervical discectomy and fusion: a retrospective study.

Zhenqi Lou, Yi Jiang, Kanling Jiang, Jieyang Zhu, Lan Lai, Zhihai Huang, Jinyu Zhu

Abstract read
In one paragraph

Article in The Journal of international medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhenqi LouDepartment of Orthopaedic Surgery, Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.ORCID 0000-0001-9855-8245
Yi JiangDepartment of Orthopaedic Surgery, Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.
Kanling JiangDepartment of Orthopaedic Surgery, Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.
Jieyang ZhuDepartment of Orthopaedic Surgery, Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.
Lan LaiDepartment of Anaesthesiology, Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.
Zhihai HuangDepartment of Orthopaedic Surgery, Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.
Jinyu ZhuDepartment of Orthopaedic Surgery, Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the safety and efficacy of intravenous tranexamic acid (TXA) administration in anterior cervical discectomy fusion (ACDF) for the treatment of cervical spondylosis in the elderly.

methodsData from elderly patients who underwent ACDF between January 2020 and January 2023 were retrospectively reviewed. Patients who received 1 g intravenous TXA administration before skin incision (TXA group) were compared with patients who did not receive TXA (controls). Total and hidden blood loss were calculated, and the following outcomes were recorded: haemoglobin and haematocrit drop, operation time, drainage duration, drain volume, length of hospitalization, coagulation changes, and incidence of complications.

resultsA total of 114 patients were included (TXA group,

conclusionsIntravenous TXA is effective in reducing perioperative blood loss in elderly patients undergoing ACDF without changing the coagulation function or increasing the risk of complications.

Indexed as

Blood Loss, SurgicalCervical VertebraeDiskectomySpinal FusionTranexamic AcidAdministration, IntravenousAgedAged, 80 and overAntifibrinolytic AgentsFemaleHumansLength of StayMaleOperative TimeRetrospective StudiesSpondylosisAntifibrinolytic AgentsTranexamic AcidAnterior cervical discectomy fusionBlood lossCervical spondylosisElderly patientsTranexamic acid

Identifiers

PMID39340253
PMCPMC11445765

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.