Evidence map›Paper›PMID 39340199›Full record

ArticleAngewandte Chemie (International ed. in English)2024

Non-Ionic Fluorosurfactants for Droplet-Based in vivo Applications.

Heidi L van de Wouw, Shuo-Ting Yen, Manon Valet, Joseph A Garcia, Carlos O Gomez, Antoine Vian, Yucen Liu, Jennifer Pollock, Petr Pospíšil, Otger Campàs and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Non-Ionic Fluorosurfactants for Droplet-Based in vivo Applications.Angewandte Chemie (International ed. in English) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Heidi L van de WouwDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 607 Charles E. Young Drive E., Los Angeles, CA 90095, USA.ORCID 0000-0002-2115-6325
Shuo-Ting YenCluster of Excellence Physics of Life, TU Dresden, Arnoldstrasse 18, 01307, Dresden, Germany.ORCID 0000-0003-4277-1965
Manon ValetCluster of Excellence Physics of Life, TU Dresden, Arnoldstrasse 18, 01307, Dresden, Germany.ORCID 0000-0002-0051-0663
Joseph A GarciaDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 607 Charles E. Young Drive E., Los Angeles, CA 90095, USA.ORCID 0000-0002-0253-3121
Carlos O GomezCluster of Excellence Physics of Life, TU Dresden, Arnoldstrasse 18, 01307, Dresden, Germany.
Antoine VianCluster of Excellence Physics of Life, TU Dresden, Arnoldstrasse 18, 01307, Dresden, Germany.
Yucen LiuDepartment of Mechanical Engineering, University of California, Santa Barbara, Santa Barbara, CA 93106, USA.
Jennifer PollockDepartment of Mechanical Engineering, University of California, Santa Barbara, Santa Barbara, CA 93106, USA.
Petr PospíšilCluster of Excellence Physics of Life, TU Dresden, Arnoldstrasse 18, 01307, Dresden, Germany.
Otger CampàsCluster of Excellence Physics of Life, TU Dresden, Arnoldstrasse 18, 01307, Dresden, Germany.ORCID 0000-0002-9642-8030
Ellen M SlettenDepartment of Chemistry and Biochemistry, University of California, Los Angeles, 607 Charles E. Young Drive E., Los Angeles, CA 90095, USA.ORCID 0000-0002-0049-7278

Funding

Robust microdroplet-based mechanical probes for wide-ranging mechanobiology applicationsR01GM135380 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CAMPAS, OTGER, SLETTEN, ELLEN MAY · 2019 to 2022
$1.8M
NMR Console and Prodigy CryoProbeS10OD028644 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GARG, NEIL K · 2021 to 2021
$600k
German Research Foundation EXC 2068-390729961Human Frontier Science Program LT000283-2020-CNIGMS NIH HHS R01 GM135380NIGMS NIH HHS R01GM135380NIH HHS S10 OD028644UCLA Cota Robles
6 · The paper itself

Abstract

Fluorocarbon oils are uniquely suited for many biomedical applications due to their inert, bioorthogonal properties. In order to interface fluorocarbon oils with biological systems, non-ionic fluorosurfactants are necessary. However, there is a paucity of non-ionic fluorosurfactants with low interfacial tension (IFT) to stabilize fluorocarbon phases in aqueous environments (such as oil-in-water emulsions). We developed non-ionic fluorosurfactants composed of a polyethylene glycol (PEG) segment covalently bonded to a flexible perfluoropolyether (PFPE) segment that confer low IFTs between a fluorocarbon oil (HFE-7700) and water. The synthesis of a panel of surfactants spanning a molecular weight range of 0.64-66 kDa with various hydrophilic-lipophilic balances allowed for identification of minimal IFTs, ranging from 1.4 to 17.8 mN m

Indexed as

FluorocarbonsPolyethylene GlycolsSurface-Active AgentsZebrafishAnimalsEthersHydrophobic and Hydrophilic InteractionsSurface TensionWaterEthersFluorocarbonsperfluoropolyetherPolyethylene GlycolsSurface-Active AgentsWaterfluorosurfactantin vivo force sensingmicrodropletsperfluoropolyethersurfactant

Identifiers

PMID39340199
PMCPMC11656150

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.