Evidence map›Paper›PMID 39340091›Full record

ArticleVaccines2024

Methotrexate and Tumor Necrosis Factor Inhibitors Independently Decrease Neutralizing Antibodies after SARS-CoV-2 Vaccination: Updated Results from the SUCCEED Study.

Carol A Hitchon, Dawn M E Bowdish, Gilles Boire, Paul R Fortin, Louis Flamand, Vinod Chandran, Roya M Dayam, Anne-Claude Gingras, Catherine M Card, Inés Colmegna and 6 more

Abstract read
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Vaccination Update and Specific Concerns for RA.Current rheumatology reports · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Carol A HitchonDepartment of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.ORCID 0000-0001-5547-3268
Dawn M E BowdishMcMaster Immunology Research Centre, McMaster University, Hamilton, ON L8S 4L8, Canada.ORCID 0000-0001-6823-2957
Gilles BoireDivision of Rheumatology, Department of Medicine, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.ORCID 0000-0003-2481-5821
Paul R FortinCentre de Recherche ARThrite-UL, Division of Rheumatology, Department of Medicine, CHU de Québec, Université Laval, Québec City, QC G1V 4G2, Canada.ORCID 0000-0002-7278-2596
Louis FlamandAxe Maladies Infectieuses et Immunitaires, Centre de Recherche du CHU de Québec, Université Laval, Québec City, QC G1V 4G2, Canada.
Vinod ChandranSchroeder Arthritis Institute and Krembil Research Institute, University Health Network, Toronto, ON M5T 2S8, Canada.
Roya M DayamLunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital, Sinai Health, Toronto, ON M5G 1X5, Canada.
Anne-Claude GingrasLunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital, Sinai Health, Toronto, ON M5G 1X5, Canada.
Catherine M CardDepartment of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
Inés ColmegnaDepartment of Medicine, McGill University, Montreal, QC H3A 0E9, Canada.
Maggie J LarchéDivision of Rheumatology, Department of Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada.
Gilaad G KaplanDivision of Gastroenterology and Hepatology, Departments of Medicine and Community Health Sciences, University of Calgary, Calgary, AB T2N 1N4, Canada.ORCID 0000-0003-2719-0556
Luck LukusaThe Research Institute of the McGill University Health Centre, McGill University, Montreal, QC H3A 0E9, Canada.ORCID 0009-0003-6435-8140
Jennifer L F LeeThe Research Institute of the McGill University Health Centre, McGill University, Montreal, QC H3A 0E9, Canada.ORCID 0000-0002-5501-0017
Sasha BernatskyDepartment of Medicine, McGill University, Montreal, QC H3A 0E9, Canada.ORCID 0000-0002-9515-2802
On Behalf Of The Succeed Investigative Team

Funding

Public Health Agency of Canada 2122-HQ-000070
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

autoimmune diseasesCOVID-19immune-mediated inflammatory diseasemethotrexateTNF-blocking antibodytumor necrosis factor inhibitorsvaccination

Identifiers

PMID39340091
PMCPMC11436066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.