Evidence map›Paper›PMID 39340074›Full record

ReviewVaccines2024

Recent Occurrence, Diversity, and Candidate Vaccine Virus Selection for Pandemic H5N1: Alert Is in the Air.

Yordanka Medina-Armenteros, Daniela Cajado-Carvalho, Ricardo das Neves Oliveira, Milena Apetito Akamatsu, Paulo Lee Ho

Abstract readReview
In one paragraph

Review in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yordanka Medina-ArmenterosCentro BioIndustrial, Instituto Butantan and Fundação Butantan, São Paulo 05503-900, SP, Brazil.ORCID 0000-0001-7941-7535
Daniela Cajado-CarvalhoCentro BioIndustrial, Instituto Butantan and Fundação Butantan, São Paulo 05503-900, SP, Brazil.ORCID 0000-0001-9234-1758
Ricardo das Neves OliveiraCentro BioIndustrial, Instituto Butantan and Fundação Butantan, São Paulo 05503-900, SP, Brazil.
Milena Apetito AkamatsuCentro BioIndustrial, Instituto Butantan and Fundação Butantan, São Paulo 05503-900, SP, Brazil.ORCID 0000-0002-8193-3448
Paulo Lee HoCentro BioIndustrial, Instituto Butantan and Fundação Butantan, São Paulo 05503-900, SP, Brazil.ORCID 0000-0003-3652-241X

Funding

Fundação Butantan N/AFundação de Amparo à Pesquisa do Estado de São Paulo 2020/07040-1National Council for Scientific and Technological Development 305430/2019-0National Council for Scientific and Technological Development 309741/2023-8National Council for Scientific and Technological Development 444400/2023-0
6 · The paper itself

Abstract

The prevalence of the highly pathogenic avian influenza virus H5N1 in wild birds that migrate all over the world has resulted in the dissemination of this virus across Asia, Europe, Africa, North and South America, the Arctic continent, and Antarctica. So far, H5N1 clade 2.3.4.4.b has reached an almost global distribution, with the exception of Australia and New Zealand for autochthonous cases. H5N1 clade 2.3.4.4.b, derived from the broad-host-range A/Goose/Guangdong/1/96 (H5N1) lineage, has evolved, adapted, and spread to species other than birds, with potential mammal-to-mammal transmission. Many public health agencies consider H5N1 influenza a real pandemic threat. In this sense, we analyzed H5N1 hemagglutinin sequences from recent outbreaks in animals, clinical samples, antigenic prototypes of candidate vaccine viruses, and licensed human vaccines for H5N1 with the aim of shedding light on the development of an H5N1 vaccine suitable for a pandemic response, should one occur in the near future.

Indexed as

A (H5N1) candidate vaccine virusA (H5) non-A (H5N1) candidate vaccine virusH5 hemagglutininH5N1 pandemic preparednessHPAI H5N1 viruspandemic H5N1 epizootic

Identifiers

PMID39340074
PMCPMC11435632

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.