Evidence map›Paper›PMID 39339963›Full record

ArticleViruses2024

Differing Transcriptomic Responses in High Titer versus Low Titer

Peter Hodoameda, Robert E Ditter, Scott R Santos, Rollie J Clem

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Peter HodoamedaDivision of Biology, Kansas State University, Manhattan, KS 66506, USA.ORCID 0000-0002-0231-296X
Robert E DitterDepartment of Biological Sciences, State University of New York at Buffalo, Buffalo, NY 14261, USA.
Scott R SantosDepartment of Biological Sciences, State University of New York at Buffalo, Buffalo, NY 14261, USA.
Rollie J ClemDivision of Biology, Kansas State University, Manhattan, KS 66506, USA.ORCID 0000-0002-2368-720X

Funding

National Science Foundation 2024024
6 · The paper itself

Abstract

Oral infection of mosquitoes by arboviruses often results in a large degree of variation in the amount of infectious virus between individual mosquitoes, even when the mosquitoes are from inbred laboratory strains. This variability in arbovirus load has been shown to affect virus transmissibility. Previously, our group described population genetic and specific infectivity differences between the virus populations found in high and low titer

Indexed as

AedesMosquito VectorsSindbis VirusTranscriptomeViral LoadAlphavirus InfectionsAnimalsFemaleGene Expression ProfilingVirus ReplicationAedes aegyptiarbovirusmosquitoSindbis virusvector competence

Identifiers

PMID39339963
PMCPMC11437473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.