Evidence map›Paper›PMID 39339869›Full record

ArticleViruses2024

Patterns of Transmitted Drug Resistance Mutations and HIV-1 Subtype Dynamics in ART-Naïve Individuals in Veneto, Italy, from 2017 to 2024.

Nicholas Geremia, Monica Basso, Andrea De Vito, Renzo Scaggiante, Mario Giobbia, Giuliana Battagin, Federico Dal Bello, Maria Teresa Giordani, Stefano Nardi, Marina Malena and 2 more

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nicholas GeremiaUnit of Infectious Diseases, Department of Clinical Medicine, Ospedale Dell'Angelo, 30174 Venice, Italy.ORCID 0000-0001-7988-5419
Monica BassoDepartment of Molecular Medicine, University of Padua, 35121 Padua, Italy.
Andrea De VitoUnit of Infectious Diseases, Department of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-8265-5400
Renzo ScaggianteUnit of Infectious Diseases, AULSS 1, 32100 Belluno, Italy.
Mario GiobbiaUnit of Infectious Diseases, AULSS 2, 35100 Treviso, Italy.
Giuliana BattaginUnit of Infectious Diseases, AULSS 8, 36100 Vicenza, Italy.
Federico Dal BelloDepartment of Molecular Medicine, University of Padua, 35121 Padua, Italy.
Maria Teresa GiordaniUnit of Infectious Diseases, AULSS 7, 36014 Santorso, Italy.ORCID 0000-0002-6674-3566
Stefano NardiUnit of Infectious Diseases, AULSS 9, 37122 Verona, Italy.
Marina MalenaUnit of Infectious Diseases, AULSS 5, 45100 Rovigo, Italy.
Annamaria CattelanDepartment of Molecular Medicine, University of Padua, 35121 Padua, Italy.
Saverio Giuseppe ParisiDepartment of Molecular Medicine, University of Padua, 35121 Padua, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the prevalence and patterns of transmitted drug resistance mutations (TDRMs) and HIV-1 subtypes among antiretroviral therapy (ART) naïve individuals in Veneto, Italy, from 2017 to 2024. This research aims to understand the dynamic landscape of TDRMs and HIV-1 genetic diversity to inform treatment strategies effectively. We included all adult ART-naïve people with HIV (PWH) from seven infectious disease units in Veneto, Italy. We collected the genotypic resistance testing conducted to predict drug susceptibility and subtype distribution using the Stanford HIVdb algorithm. We included 762 PWH, showing a slight but statistically significant decline in the B subtype among Italian PWH (

Indexed as

Anti-HIV AgentsDrug Resistance, ViralGenotypeHIV-1HIV InfectionsMutationAdultFemaleGenetic VariationHumansItalyMaleMiddle AgedPrevalenceYoung AdultAnti-HIV Agentsgenotypic resistance testingHIVHIV resistanceHIV subtypestransmitted drug resistance mutations

Identifiers

PMID39339869
PMCPMC11437434

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.